When Blood Breaks Down Book

When Blood Breaks Down


  • Author : Mikkael A. Sekeres
  • Publisher : MIT Press
  • File Size : 13,7 Mb
  • Release Date : 2021-08-17
  • Genre: Medical
  • Pages : 325
  • ISBN 10 : 9780262542258

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A leading cancer specialist tells the compelling stories of three adult leukemia patients, shedding new light on the disease itself and the drugs developed to treat it When you are told that you have leukemia, your world stops. Your brain can’t function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together. Sekeres, who writes regularly for the “Well” section of The New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family’s wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimate conversations between Sekeres and his patients, and we watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it—describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia. The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

Drugs and the FDA Book

Drugs and the FDA


  • Author : Mikkael A. Sekeres
  • Publisher : MIT Press
  • File Size : 17,5 Mb
  • Release Date : 2022-09-27
  • Genre: Medical
  • Pages : 319
  • ISBN 10 : 9780262371315

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How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer’s drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug’s safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA’s cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world. It took a series of tragedies and health crises, as well as patient advocacy, for the government to take responsibility for ensuring the efficacy and safety of drugs and medical devices. Before the FDA existed, drug makers could hawk any potion, claim treatment of any ailment, and make any promise on a label. But then, throughout the twentieth century, the government was forced to take action when children were poisoned by contaminated diphtheria and smallpox vaccines, an early antibiotic contained antifreeze, a drug prescribed for morning sickness in pregnancy caused babies to be born disfigured, and access to AIDS drugs was limited to a few clinical trials while thousands died. Sekeres describes all these events against the backdrop of the contentious 2011 hearings on the breast cancer drug Avastin, in which he participated as a panel member. The Avastin hearings, he says, put to the test a century of the FDA’s evolution, demonstrating how its system of checks and balances works—or doesn’t work.

A Manual for the practice of surgery Book

A Manual for the practice of surgery


  • Author : Thomas Bryant
  • Publisher : Unknown
  • File Size : 8,7 Mb
  • Release Date : 1885
  • Genre: Uncategoriezed
  • Pages : 1072
  • ISBN 10 : STANFORD:24501634394

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The Dublin Journal of Medical Science Book

The Dublin Journal of Medical Science


  • Author : Anonim
  • Publisher : Unknown
  • File Size : 18,8 Mb
  • Release Date : 1884
  • Genre: Medicine
  • Pages : 576
  • ISBN 10 : OXFORD:555022321

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Encyclopaedia Medica Book

Encyclopaedia Medica


  • Author : Chalmers Watson
  • Publisher : Unknown
  • File Size : 6,6 Mb
  • Release Date : 1899
  • Genre: Medicine
  • Pages : null
  • ISBN 10 : UCAL:B4210335

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Fevers  Feuds  and Diamonds Book
Score: 4
From 3 Ratings

Fevers Feuds and Diamonds


  • Author : Paul Farmer
  • Publisher : Farrar, Straus and Giroux
  • File Size : 14,7 Mb
  • Release Date : 2020-11-17
  • Genre: Medical
  • Pages : 688
  • ISBN 10 : 9780374716981

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“Paul Farmer brings his considerable intellect, empathy, and expertise to bear in this powerful and deeply researched account of the Ebola outbreak that struck West Africa in 2014. It is hard to imagine a more timely or important book.” —Bill and Melinda Gates "[The] history is as powerfully conveyed as it is tragic . . . Illuminating . . . Invaluable." —Steven Johnson, The New York Times Book Review In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand—Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa’s chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not – and the region’s health care woes worsened, with devastating consequences that Farmer traces up to the present. This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.

Journal of the American Medical Association Book

Journal of the American Medical Association


  • Author : Anonim
  • Publisher : Unknown
  • File Size : 20,8 Mb
  • Release Date : 1915
  • Genre: Electronic journals
  • Pages : 1130
  • ISBN 10 : UCLA:31158004476031

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Diagnostic Neuroradiology Book

Diagnostic Neuroradiology


  • Author : Juan M. Taveras
  • Publisher : Unknown
  • File Size : 8,9 Mb
  • Release Date : 1976
  • Genre: Nervous system
  • Pages : 792
  • ISBN 10 : UOM:39015000279284

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At Night All Blood Is Black Book
Score: 4
From 9 Ratings

At Night All Blood Is Black


  • Author : David Diop
  • Publisher : Farrar, Straus and Giroux
  • File Size : 18,8 Mb
  • Release Date : 2020-11-10
  • Genre: Fiction
  • Pages : 160
  • ISBN 10 : 9780374720476

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*WINNER OF THE 2021 INTERNATIONAL BOOKER PRIZE* *ONE OF PRESIDENT BARACK OBAMA'S FAVORITE BOOKS OF 2021* Winner of the Los Angeles Times Book Prize for fiction Shortlisted for the 2022 DUBLIN Literary Award "Astonishingly good." —Lily Meyer, NPR "So incantatory and visceral I don’t think I’ll ever forget it." —Ali Smith, The Guardian | Best Books of 2020 One of The Wall Street Journal's 11 best books of the fall | One of The A.V. Club's fifteen best books of 2020 |A Sunday Times best book of the year Selected by students across France to win the Prix Goncourt des Lycéens, David Diop’s English-language, historical fiction debut At Night All Blood is Black is a “powerful, hypnotic, and dark novel” (Livres Hebdo) of terror and transformation in the trenches of the First World War. Alfa Ndiaye is a Senegalese man who, never before having left his village, finds himself fighting as a so-called “Chocolat” soldier with the French army during World War I. When his friend Mademba Diop, in the same regiment, is seriously injured in battle, Diop begs Alfa to kill him and spare him the pain of a long and agonizing death in No Man’s Land. Unable to commit this mercy killing, madness creeps into Alfa’s mind as he comes to see this refusal as a cruel moment of cowardice. Anxious to avenge the death of his friend and find forgiveness for himself, he begins a macabre ritual: every night he sneaks across enemy lines to find and murder a blue-eyed German soldier, and every night he returns to base, unharmed, with the German’s severed hand. At first his comrades look at Alfa’s deeds with admiration, but soon rumors begin to circulate that this super soldier isn’t a hero, but a sorcerer, a soul-eater. Plans are hatched to get Alfa away from the front, and to separate him from his growing collection of hands, but how does one reason with a demon, and how far will Alfa go to make amends to his dead friend? Peppered with bullets and black magic, this remarkable

Nutrition Forum Book

Nutrition Forum


  • Author : Anonim
  • Publisher : Unknown
  • File Size : 20,5 Mb
  • Release Date : 1984
  • Genre: Health products
  • Pages : 406
  • ISBN 10 : PSU:000067708697

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Caffeine for the Sustainment of Mental Task Performance Book

Caffeine for the Sustainment of Mental Task Performance


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • File Size : 6,5 Mb
  • Release Date : 2002-01-07
  • Genre: Medical
  • Pages : 172
  • ISBN 10 : 9780309082587

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This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.

Contemporary Management of Myeloproliferative Neoplasms Book

Contemporary Management of Myeloproliferative Neoplasms


  • Author : Brady L Stein
  • Publisher : Jaypee Brothers Medical Publishers Pvt. Limited
  • File Size : 14,9 Mb
  • Release Date : 2014-11-30
  • Genre: Medical
  • Pages : 0
  • ISBN 10 : 9351523624

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Myeloproliferative neoplasms (MPN) are a group of blood disorders related to leukaemia in which the body makes too many blood cells. MPN originates in the bone marrow - the soft tissue in the middle of the bones, where all the blood cells are made. In patients with MPN, normal blood cell production breaks down and the bone marrow becomes over-active and makes far too many blood cells. This can cause the blood to become thick. MPN can affect any of the blood cells (red, white and platelets) (Leukemia & Lymphona Research). This book is a comprehensive guide to the diagnosis and management of MPN. Beginning with an introduction, the following chapters examine the diagnostic classification, epidemiology, clinical features and treatment of different types of MPN. A complete chapter is dedicated to hematopoietic stem cell transplant in myelofibrosis. Edited by authoritative experts from Northwestern University Feinberg School of Medicine, Chicago, this useful reference is enhanced by detailed images, illustrations and tables. Key points Comprehensive guide to diagnosis and treatment of myeloproliferative neoplasms Covers diagnostic classification, epidemiology, clinical features and treatment of different types of MPN Complete chapter dedicated to hematopoietic stem cell transplant Edited by recognised experts from Northwestern University Feinberg School of Medicine, Chicago

MCAT Comprehensive Review Book

MCAT Comprehensive Review


  • Author : Anonim
  • Publisher : Unknown
  • File Size : 14,7 Mb
  • Release Date : 2000
  • Genre: Medical colleges
  • Pages : 1098
  • ISBN 10 : PSU:000045985201

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Commentary on Hippocrates  Aphorisms Book

Commentary on Hippocrates Aphorisms


  • Author : Stephanus (of Alexandria.)
  • Publisher : Unknown
  • File Size : 19,5 Mb
  • Release Date : 1985
  • Genre: Medicine, Greek and Roman
  • Pages : 266
  • ISBN 10 : STANFORD:36105008375409

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