Translational Biotechnology Book

Translational Biotechnology

  • Author : Yasha Hasija
  • Publisher : Academic Press
  • File Size : 20,5 Mb
  • Release Date : 2021-01-17
  • Genre: Business & Economics
  • Pages : 452
  • ISBN 10 : 9780128219737
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Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Translational Bioinformatics in Healthcare and Medicine Book

Translational Bioinformatics in Healthcare and Medicine

  • Author : Anonim
  • Publisher : Academic Press
  • File Size : 9,8 Mb
  • Release Date : 2021-05-13
  • Genre: Business & Economics
  • Pages : 254
  • ISBN 10 : 9780323898904
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Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Biotechnology Entrepreneurship Book

Biotechnology Entrepreneurship

  • Author : Craig Shimasaki
  • Publisher : Academic Press
  • File Size : 10,9 Mb
  • Release Date : 2020-05-16
  • Genre: Medical
  • Pages : 682
  • ISBN 10 : 9780128155868
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This second edition of Biotechnology Entrepreneurship: Leading, Managing, and Commercializing Innovative Technologies is an authoritative, easy-to-read guide covering biotechnology entrepreneurship and the process of commercializing innovative biotechnology products. This best practice resource is for professional training programs, individuals starting a biotech venture, and for managers and experienced practitioners leading biotech enterprises. It is a valuable resource for those working at any level in the biotech industry, and for professionals who support and provide essential resources and services to the biotech industry. This practical, “how-to book is written by seasoned veterans experienced in each of the operational functions essential for starting, managing, and leading a successful biotech company. Biotechnology Entrepreneurship explains the biotech business components and underlying strategies, interspersed with practical lessons from successful biotech entrepreneurs, educators, and experienced practitioners. These veteran contributors share their insights on how to be successful in this challenging but exciting industry. Subjects range from technology licensing and translating an idea into a viable business, forming your legal company entity, securing angel and venture capital, navigating product development, FDA regulatory approval, and biomanufacturing. This book is a user-friendly guide to decision-making and overall strategy written as a hands-on management tool for leaders and managers of these dynamic biotechnology ventures. If you are contemplating starting a biotech company, are a manager at any level, a seasoned veteran, or service provider in the biotech industry, this book is a “must read. This second edition includes several new chapters on topics such as: What you need to know about valuation and term sheets Investor presentations and what you need in a biotech investor pitch deck Mentorship and why you need mentors Artificial intelli

Clinical and Translational Science Book

Clinical and Translational Science

  • Author : David Robertson
  • Publisher : Academic Press
  • File Size : 11,5 Mb
  • Release Date : 2016-11-25
  • Genre: Science
  • Pages : 808
  • ISBN 10 : 9780128021118
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Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Handbook of translational medicine Book

Handbook of translational medicine

  • Author : Josep M. Llovet
  • Publisher : Edicions Universitat Barcelona
  • File Size : 7,5 Mb
  • Release Date : 2016-10-05
  • Genre: Medical
  • Pages : 245
  • ISBN 10 : 9788447540303
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This handbook aims to capture the basic concepts of translational medicine, understood as a branch of the biomedical field that translates discoveries into the clinical setting. This discipline is currently closing the gap between basic science and clinical research. The book is intended to be straightforward, easy-to-read, intelligible and practical. It describes the basic principles of translational medicine, including major advances in genomics, new technologies, the processing of big data and biobanks. Regarding the biological foundations of translational medicine, we address concepts related to the molecular basis of cancer, inflammation, angiogenesis, stem cells and experimental models. More specifically on translational medicine, we present discoveries and breakthroughs in oncology, neuroscience, metabolic and systemic diseases, and public health. Finally, we have specific sections focused on clinical trials and biomarkers in the genomic era, advances in imaging techniques and entrepreneurship and innovation. Our purpose is to offer a manageable text to guide graduate and post-graduate students, professionals and researchers in biomedicine through the major technologies and advances that have occurred in the translational field. It is also intended to aid residents, fellows and physician-scientists working in hospitals and academic institutions.

Principles of Translational Science in Medicine Book

Principles of Translational Science in Medicine

  • Author : Martin Wehling
  • Publisher : Academic Press
  • File Size : 10,8 Mb
  • Release Date : 2021-07-15
  • Genre: Science
  • Pages : 494
  • ISBN 10 : 9780323999625
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Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Information Retrieval in Bioinformatics Book

Information Retrieval in Bioinformatics

  • Author : Soumi Dutta
  • Publisher : Springer Nature
  • File Size : 9,5 Mb
  • Release Date : 2022
  • Genre: Bioinformatics
  • Pages : 167
  • ISBN 10 : 9789811965067
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The book presents the results of studies on selected problems (such as predictive model of transcription initiation and termination, protein recognition codes, protein structure prediction, feature selection for disease prediction, information retrieval from medical imaging) of Bioinformatics and Information Retrieval. Information Retrieval is one of the contemporary answers to new challenges in threat evaluation of composite systems. This book provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. It describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles. It presents walk-throughs of data analysis tasks using different tools to help in taking decisions in healthcare management.

Animal Biotechnology Book

Animal Biotechnology

  • Author : Ashish S. Verma
  • Publisher : Academic Press
  • File Size : 17,7 Mb
  • Release Date : 2020-06-23
  • Genre: Medical
  • Pages : 798
  • ISBN 10 : 9780128117101
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Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

The Market in Mind Book

The Market in Mind

  • Author : Mark Dennis Robinson
  • Publisher : MIT Press
  • File Size : 19,9 Mb
  • Release Date : 2019-07-23
  • Genre: Science
  • Pages : 324
  • ISBN 10 : 9780262352970
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A critical examination of translational medicine, when private risk is transferred to the public sector and university research teams become tech startups for global investors. A global shift has secretly transformed science and medicine. Starting in 2003, biomedical research in the West has been reshaped by the emergence of translational science and medicine—the idea that the aim of research is to translate findings as quickly as possible into medical products. In The Market in Mind, Mark Dennis Robinson charts this shift, arguing that the new research paradigm has turned university research teams into small biotechnology startups and their industry partners into early-stage investment firms. There is also a larger, surprising consequence from this shift: according to Robinson, translational science and medicine enable biopharmaceutical firms, as part of a broader financial strategy, to outsource the riskiest parts of research to nonprofit universities. Robinson examines the implications of this new configuration. What happens, for example, when universities absorb unknown levels of risk? Robinson argues that in the years since the global financial crisis translational science and medicine has brought about “the financialization of health.” Robinson explores such topics as shareholder anxiety and industry retreat from Alzheimer's and depression research; how laboratory research is understood as health innovation even when there is no product; the emergence of investor networking events as crucial for viewing science in a market context; and the place of patients in research decisions. Although translational medicine justifies itself by the goal of relieving patients' suffering, Robinson finds patients' voices largely marginalized in translational neuroscience.

Biochemical and Environmental Applications Book

Biochemical and Environmental Applications

  • Author : Ponnadurai Ramasami
  • Publisher : Walter de Gruyter GmbH & Co KG
  • File Size : 20,8 Mb
  • Release Date : 2022-10-03
  • Genre: Technology & Engineering
  • Pages : 234
  • ISBN 10 : 9783110783629
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Chapters collected from “The Virtual Conference on Chemistry and its Applications (VCCA-2021) – Research and Innovations in Chemical Sciences: Paving the Way Forward”. This conference was held in August 2021 and organized by the Computational Chemistry Group of the University of Mauritius. These peer-reviewed chapters offer insights into research on fundamental and applied chemistry with interdisciplinary subject matter.

Methods in Biotechnology Book

Methods in Biotechnology

  • Author : Seung-Beom Hong
  • Publisher : John Wiley & Sons
  • File Size : 10,5 Mb
  • Release Date : 2016-08-01
  • Genre: Science
  • Pages : 386
  • ISBN 10 : 9781119156789
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As rapid advances in biotechnology occur, there is a need for a pedagogical tool to aid current students and laboratory professionals in biotechnological methods; Methods in Biotechnology is an invaluable resource for those students and professionals. Methods in Biotechnology engages the reader by implementing an active learning approach, provided advanced study questions, as well as pre- and post-lab questions for each lab protocol. These self-directed study sections encourage the reader to not just perform experiments but to engage with the material on a higher level, utilizing critical thinking and troubleshooting skills. This text is broken into three sections based on level – Methods in Biotechnology, Advanced Methods in Biotechnology I, and Advanced Methods in Biotechnology II. Each section contains 14-22 lab exercises, with instructor notes in appendices as well as an answer guide as a part of the book companion site. This text will be an excellent resource for both students and laboratory professionals in the biotechnology field.

Advances in Bioartificial Materials and Tissue Engineering Research and Application 2012 Edition Book

Advances in Bioartificial Materials and Tissue Engineering Research and Application 2012 Edition

  • Author : Anonim
  • Publisher : ScholarlyEditions
  • File Size : 8,7 Mb
  • Release Date : 2012-12-26
  • Genre: Technology & Engineering
  • Pages : 827
  • ISBN 10 : 9781464991462
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Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioartificial Materials and Tissue Engi. The editors have built Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioartificial Materials and Tissue Engi in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Human Microbiome in Health and Disease Part A Book

Human Microbiome in Health and Disease Part A

  • Author : Anonim
  • Publisher : Elsevier
  • File Size : 5,8 Mb
  • Release Date : 2022-10-01
  • Genre: Science
  • Pages : 290
  • ISBN 10 : 9780323997874
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Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more. These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format. Covers the structure, functions and diversity of human microbiome in health and disease Includes discussions on drug metabolisms and microbiome based therapeutics Presents emerging tools for understanding the human microbiome

Human Microbiome in Health and Disease Part B Book

Human Microbiome in Health and Disease Part B

  • Author : Anonim
  • Publisher : Academic Press
  • File Size : 5,7 Mb
  • Release Date : 2022-11-01
  • Genre: Science
  • Pages : 356
  • ISBN 10 : 9780323913218
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Human Microbiome in Health and Disease, Volume 192, Part B includes chapters surrounding the role of human microbiome in different diseases. Chapters in this comprehensive new volume include The microbiome and communicable diseases, Gut Microbiome and Antimicrobial Resistance in bacterial pathogens, Dysbiosis of human microbiome and infectious disease, Gastrointestinal microbiome in the context of infection in stomach and gastroduodenal diseases, Respiratory tract microbiome and pneumonia, Gut microbiome and neonatal sepsis, Diarrheal disease and gut microbiome, The microbiome and non-communicable diseases, Gut microbiome and inflammatory bowel disease, Gut microbiome and undernutrition, Human microbiome and cardiovascular disease, and much more. Covers dysbiosis of microbiome in communicable and non-communicable diseases Discusses the emergence and spread of antimicrobial resistance in gut microbiome Presents the latest information on reproductive tract microbiome and birth outcomes

Translational Toxicology Book

Translational Toxicology

  • Author : Claude L. Hughes
  • Publisher : Humana Press
  • File Size : 17,6 Mb
  • Release Date : 2016-03-23
  • Genre: Medical
  • Pages : 380
  • ISBN 10 : 9783319274492
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Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.