The Hypothalamus Pituitary Adrenal Axis Book

The Hypothalamus Pituitary Adrenal Axis


  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2008-09-12
  • Genre: Medical
  • Pages : 416
  • ISBN 10 : 0080559360
  • Total Read : 85
  • File Size : 19,6 Mb

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The Hypothalamus Pituitary Adrenal Axis Summary:

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.

Anxiety Disorders Book

Anxiety Disorders


  • Author : Kerry Ressler
  • Publisher : Oxford University Press
  • Release Date : 2015-04-15
  • Genre: Medical
  • Pages : 448
  • ISBN 10 : 9780199395132
  • Total Read : 72
  • File Size : 15,6 Mb

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Anxiety Disorders Summary:

Anxiety affects millions, manifesting as generalized anxiety disorder (GAD), obsessive compulsive disorder, panic disorder, phobias, post-traumatic-stress disorder (PTSD), and social anxiety disorder. Not only are anxiety disorders common, but they are also crippling, frequently co-occurring and predict high risk for depressive disorders. Shared mechanisms may explain the overlapping features of many anxiety disorders and account for associations with other highly-impairing conditions, such as major depression and substance use. Beyond risk for specific disorders, anxiety also predicts a number of other adverse outcomes, including suicidal behavior, medical problems, social, and economic difficulties. Conversely, disorder-specific mechanisms may also exist and explain the unique features of each syndrome. Thus, it is important to understand both shared and specific aspects of anxiety. The Primer on Anxiety Disorders provides early-stage practitioners and trainees, as well as seasoned clinicians and researchers, with need-to-know knowledge on diagnosis and treatment. Clinical cases are used throughout the book to enhance understanding of and illustrate specific disorders, comorbid conditions and clinical issues. To facilitate an integrative approach, content allows clinicians to understand patient characteristics and tailor interventions. The integrated approach of each chapter includes recent research on genetics and neuroscience to understand the mechanisms of anxiety disorders, focusing on the forthcoming new nosology in DSM-5. Chapters further integrate innovative advances in clinical research providing research on a range of discoveries regarding biomarkers of illness, biological predictors of treatments and the effect of treatment on neurocircuitry.

Clinical Neuroendocrinology Book

Clinical Neuroendocrinology


  • Author : Michael Wilkinson
  • Publisher : Cambridge University Press
  • Release Date : 2019-01-03
  • Genre: Medical
  • Pages : 207
  • ISBN 10 : 9781316645192
  • Total Read : 85
  • File Size : 19,6 Mb

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Clinical Neuroendocrinology Summary:

A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.

A Time for Metabolism and Hormones Book

A Time for Metabolism and Hormones


  • Author : Paolo Sassone-Corsi
  • Publisher : Springer
  • Release Date : 2016-04-04
  • Genre: Medical
  • Pages : 132
  • ISBN 10 : 9783319270692
  • Total Read : 62
  • File Size : 10,8 Mb

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A Time for Metabolism and Hormones Summary:

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Sports Endocrinology Book

Sports Endocrinology


  • Author : F. Lanfranco
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2016-06-28
  • Genre: Medical
  • Pages : 172
  • ISBN 10 : 9783318058697
  • Total Read : 64
  • File Size : 13,7 Mb

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Sports Endocrinology Summary:

This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.

ACTH Action in the Adrenal Cortex  From Molecular Biology to Pathophysiology Book

ACTH Action in the Adrenal Cortex From Molecular Biology to Pathophysiology


  • Author : Nicole Gallo-Payet
  • Publisher : Frontiers Media SA
  • Release Date : 2017-07-27
  • Genre: ACTH.
  • Pages : 421
  • ISBN 10 : 9782889452323
  • Total Read : 63
  • File Size : 12,8 Mb

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ACTH Action in the Adrenal Cortex From Molecular Biology to Pathophysiology Summary:

By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still repre

The Hypothalamic Pituitary Adrenal Axis in Health and Disease Book

The Hypothalamic Pituitary Adrenal Axis in Health and Disease


  • Author : Eliza B. Geer
  • Publisher : Springer
  • Release Date : 2016-12-01
  • Genre: Medical
  • Pages : 327
  • ISBN 10 : 9783319459509
  • Total Read : 75
  • File Size : 9,8 Mb

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The Hypothalamic Pituitary Adrenal Axis in Health and Disease Summary:

Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

The Hypothalamus pituitary adrenal Axis Book

The Hypothalamus pituitary adrenal Axis


  • Author : Adriana Del Rey
  • Publisher : Elsevier Science
  • Release Date : 2008
  • Genre: Medical
  • Pages : 394
  • ISBN 10 : 0444530401
  • Total Read : 65
  • File Size : 20,8 Mb

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The Hypothalamus pituitary adrenal Axis Summary:

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.