The Genome Odyssey Book
Score: 4
From 3 Ratings

The Genome Odyssey

  • Author : Dr. Euan Angus Ashley
  • Publisher : Celadon Books
  • File Size : 13,5 Mb
  • Release Date : 2021-02-23
  • Genre: Science
  • Pages : 217
  • ISBN 10 : 9781250234971


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In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the gen

The Genome Odyssey Book
Score: 4
From 2 Ratings

The Genome Odyssey

  • Author : Dr. Euan Angus Ashley
  • Publisher : Celadon Books
  • File Size : 12,7 Mb
  • Release Date : 2021-02-23
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 1250234999


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The Journey of Man Book
Score: 4
From 3 Ratings

The Journey of Man

  • Author : Spencer Wells
  • Publisher : Princeton University Press
  • File Size : 10,9 Mb
  • Release Date : 2017-03-28
  • Genre: Reference
  • Pages : 238
  • ISBN 10 : 9780691176017


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Around 60,000 years ago, a man, genetically identical to us, lived in Africa. Every person alive today is descended from him. How did this real-life Adam wind up as the father of us all? What happened to the descendants of other men who lived at the same time? And why, if modern humans share a single prehistoric ancestor, do we come in so many sizes, shapes, and races? Examining the hidden secrets of human evolution in our genetic code, the author reveals how developments in the revolutionary science of population genetics have made it possible to create a family tree for the whole of humanity. Replete with marvelous anecdotes and remarkable information, from the truth about the real Adam and Eve to the way differing racial types emerged, this book is an enthralling, epic tour through the history and development of early humankind.

Bovine Genomics Book

Bovine Genomics

  • Author : James Womack
  • Publisher : John Wiley & Sons
  • File Size : 19,7 Mb
  • Release Date : 2012-03-16
  • Genre: Science
  • Pages : 284
  • ISBN 10 : 9781118301708


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The genetic information being unlocked by advances in genomic and high throughput technologies is rapidly revolutionizing our understanding of developmental processes in bovine species. This information is allowing researchers unprecedented insight into the genetic basis of key traits. Bovine Genomics is the first book to bring together and synthesize the information learned through the bovine genome sequencing project and look at its practical application to cattle and dairy production. Bovine Genomics opens with foundational chapters on the domestication of cattle and traditional Mendelian genetics. Building on these chapters, coverage rapidly moves to quantitative genetics and the advances of whole genome technologies. Significant coverage is given to such topics as epigenetics, mapping quantitative trail loci, genome-wide association studies and genomic selection in cattle breeding. The book is a valuable synthesis of the field written by a global team of leading researchers. Providing wide-ranging coverage of the topic, Bovine Genomic, is an essential guide to the field. The basic and applied science will be of use to researchers, breeders, and advanced students.

The Genome Generation Book
Score: 5
From 1 Ratings

The Genome Generation

  • Author : Elizabeth Finkel
  • Publisher : Melbourne Univ. Publishing
  • File Size : 11,6 Mb
  • Release Date : 2012
  • Genre: Science
  • Pages : 290
  • ISBN 10 : 9780522856477


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The year 2001 marked more than just the beginning of Stanley Kubrick's Space Odyssey, it marked the beginning of the genome era. That was the year scientists first read the 3 billion letters of DNA that make up the human genome. This was followed by a veritable Noah's Ark of genomesandmdash;sponges and worms, dogs and cows, rice and wheat, chimps and elephantsandmdash;180 creatures aboard so far. So what have we learned from all this? How has it changed the way we practise medicine, grow crops and breed livestock? What have we learned about evolution? These are the questions science writer and molecular biologist Elizabeth Finkel asked herself four years ago. To find the answers she travelled the science frontier from Botswana to Boston, from Warracknabeal to Mexico and tracked down scientists working in the field. Their stories, told here, paint the picture of what it means to be part of the genome generation. 'The Genome Generation is absolutely riveting. These tales from the frontier are a 'must read' for everyone who wishes to understand our pastandmdash;the logic of evolutionandmdash;or take a peep into our exciting future at the creation of 'super plants' through 'digital agriculture'.'andmdash;R.A. Mashelkar, CSIR Bhatnagar Fellow and India President, Global Research Alliance

Medical and Health Genomics Book

Medical and Health Genomics

  • Author : Dhavendra Kumar
  • Publisher : Academic Press
  • File Size : 12,5 Mb
  • Release Date : 2016-06-04
  • Genre: Science
  • Pages : 358
  • ISBN 10 : 9780127999227


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Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Olive Odyssey Book

Olive Odyssey

  • Author : Julie Angus
  • Publisher : Greystone Books
  • File Size : 16,8 Mb
  • Release Date : 2014-05-05
  • Genre: Biography & Autobiography
  • Pages : 344
  • ISBN 10 : 9781771000062


Download Olive Odyssey Book in PDF and ePub

This Mediterranean travel memoir offers “an engaging mix of history, food travelogue, and botany lesson . . . There is much to enjoy here” (Library Journal). Inspired by her Syrian forebears’ intimate relationship with the olive, Julie Angus embarks on a voyage around the Mediterranean to unlock the secrets of the fruit that meant so much to them. Accompanied by her husband and their ten-month-old son, Angus collects samples from ancient trees to determine where the first olive tree originated; feasts on inky black tapenades and codfish drizzled with olive oil, among many other delights; witnesses the harvesting of olives in Greece; and visits perhaps the oldest olive tree in the world, on Crete. The result is a fascinating history and biography of this most influential and irresistible fruit. “It is a pleasure to try to keep up with this book; like its author, it covers an enormous amount of territory.” —Christopher Bakken, Wall Street Journal

The Human Odyssey Book
Score: 4
From 2 Ratings

The Human Odyssey

  • Author : Thomas Armstrong
  • Publisher : Courier Dover Publications
  • File Size : 6,5 Mb
  • Release Date : 2019-03-20
  • Genre: Psychology
  • Pages : 368
  • ISBN 10 : 9780486838885


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Thomas Armstrong, Ph.D., an award-winning educator and expert on human development, offers a cross-cultural view of life's entire journey, from before birth to death to the possibilities of an afterlife. Dr. Armstrong cites both clinical research and anecdotal evidence in a comprehensive view of the challenges and opportunities we face at every stage of our development. His accessible narrative incorporates elements of history, literature, psychology, spirituality, and science in a fascinating guide to understanding our past as well as our future. - "Thomas Armstrong's The Human Odyssey is an extraordinary book; an intellectual feast. Armstrong has amassed and integrated an amazing amount of information from developmental and transpersonal psychology, modern consciousness research, biology, anthropology, mythology, and art, and created an extraordinary guide through all the stages of the adventure of human life. While the rich content of this book will impress professional audiences, it's clear and easy style makes it quite accessible to the general public." — Stanislav Grof, M.D., former Chief of Psychiatric Research, Maryland Psychiatric Research Center; author of Realms of the Human Unconscious, Beyond the Brain: Birth, Death, and Transcendence in Psychotherapy and Adventures in Self-Discovery

Genomics in the Cloud Book

Genomics in the Cloud

  • Author : Geraldine A. Van der Auwera
  • Publisher : O'Reilly Media
  • File Size : 14,9 Mb
  • Release Date : 2020-04-02
  • Genre: Computers
  • Pages : 496
  • ISBN 10 : 9781491975169


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Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytes—or over 50 million gigabytes—of genomic data, and they’re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian O’Connor of the UC Santa Cruz Genomics Institute, guide you through the process. You’ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra

Virolution Book
Score: 4
From 1 Ratings


  • Author : Frank Ryan
  • Publisher : HarperCollins UK
  • File Size : 11,9 Mb
  • Release Date : 2013-11-28
  • Genre: Science
  • Pages : 400
  • ISBN 10 : 9780007545278


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The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.

Advancing Disease Modeling in Animal Based Research in Support of Precision Medicine Book

Advancing Disease Modeling in Animal Based Research in Support of Precision Medicine

  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • File Size : 18,9 Mb
  • Release Date : 2018-06-29
  • Genre: Science
  • Pages : 139
  • ISBN 10 : 9780309471169


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Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.

The Postgenomic Condition Book

The Postgenomic Condition

  • Author : Jenny Reardon
  • Publisher : University of Chicago Press
  • File Size : 6,6 Mb
  • Release Date : 2017-12-29
  • Genre: Philosophy
  • Pages : 320
  • ISBN 10 : 9780226510453


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The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue

Economic Evaluation in Genomic Medicine Book

Economic Evaluation in Genomic Medicine

  • Author : Vasilios Fragoulakis
  • Publisher : Academic Press
  • File Size : 14,9 Mb
  • Release Date : 2015-03-20
  • Genre: Science
  • Pages : 174
  • ISBN 10 : 9780128016114


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Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists. Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process. The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of economic evaluation to genomic healthcare and precision medicine. Interrelates economic evaluation and genomic medicine Instructs healthcare professionals and bioscientists about economic evaluation in genomic medicine Teaches health economists about application of economic evaluation in genomic medicine Introduces health economics and economic evaluation to clinicians and researchers involved in genomics Includes process guides, maps, flow charts and diagrams

Rare Diseases Book

Rare Diseases

  • Author : Mani T. Valarmathi
  • Publisher : BoD – Books on Demand
  • File Size : 19,5 Mb
  • Release Date : 2021-09-22
  • Genre: Medical
  • Pages : 152
  • ISBN 10 : 9781839629303


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A rare disease is any disease or condition that affects a small percentage of the population. Many rare conditions are life-threatening or chronically debilitating, and unfortunately do not have appropriate treatments, rendering them incurable. In recent years, there has been substantial development in the area of rare disease research and its clinical applications, for instance, rare disease biology and genomics, epidemiology and preventions, early detection and screening, and diagnosis and treatment. In this context, this book consolidates the recent advances in rare disease biology and therapeutics, covering a wide spectrum of interrelated topics, and disseminates this essential knowledge in a comprehensible way to a greater scientific and clinical audience as well as patients, caregivers, and drug and device manufacturers, especially to support rare disease product development. Chapters cover such diseases as Felty’s syndrome, Löfgren’s syndrome, mesothelioma, epidermolysis bullosa, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.

The Amaranth Genome Book

The Amaranth Genome

  • Author : Dinesh Adhikary
  • Publisher : Springer Nature
  • File Size : 7,9 Mb
  • Release Date : 2021-06-01
  • Genre: Science
  • Pages : 181
  • ISBN 10 : 9783030723651


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This book describes the development of genetic resources in amaranths, with a major focus on genomics, reverse, and forward genetics tools and strategies that have been developed for crop improvement. Amaranth is an ancient crop native to the New World. Interest in amaranths is being renewed, due to their adaptability, stress tolerance, and nutritional value. There are about 65 species in the genus, including Amaranthus caudatus L., A. cruentus L., and A. hypochondriacus L., which are primarily grown as protein-rich grains or pseudocereals. The genus also includes major noxious weeds (e.g., A. palmeri). The amaranths are within the Caryophyllales order and thus many species (e.g., A. tricolor) produce red (betacyanin) or yellow (betaxanthin) betalain pigments, which are chemically distinct from the anthocyanins responsible for red pigmentation in other plants. A. hypochondriacus, which shows disomic inheritance (2n = 32; n= 466 Mb), has been sequenced and annotated with 23,059 protein-coding genes. Additional members of the genus are now also been sequenced including weedy amaranths, other grain amaranths, and their putative progenitors.