Signal Transduction Book

Signal Transduction


  • Author : Bastien D. Gomperts
  • Publisher : Gulf Professional Publishing
  • Release Date : 2003-10-15
  • Genre: Medical
  • Pages : 444
  • ISBN 10 : 0122896327
  • Total Read : 82
  • File Size : 19,9 Mb

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Signal Transduction Summary:

Signal Transduction now in paperback, is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix, etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particulary cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources key observations and experiments that set the scence for recent and current work. * Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine * Conceptual colour artwork assists with the comprehension of key topics * Extensive referencing provides an invaluable link to the core and historical literature * Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms

Signal Transduction Book

Signal Transduction


  • Author : Lewis C. Cantley
  • Publisher : Unknown
  • Release Date : 2014-05-31
  • Genre: Science
  • Pages : 452
  • ISBN 10 : 0879699019
  • Total Read : 60
  • File Size : 12,6 Mb

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Signal Transduction Summary:

"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--

Biochemistry of Signal Transduction and Regulation Book

Biochemistry of Signal Transduction and Regulation


  • Author : Gerhard Krauss
  • Publisher : John Wiley & Sons
  • Release Date : 2006-03-06
  • Genre: Science
  • Pages : 558
  • ISBN 10 : 9783527605767
  • Total Read : 95
  • File Size : 18,6 Mb

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Biochemistry of Signal Transduction and Regulation Summary:

This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)

Signal Transduction  Pathways  Mechanisms and Diseases Book

Signal Transduction Pathways Mechanisms and Diseases


  • Author : Ari Sitaramayya
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-12-02
  • Genre: Science
  • Pages : 437
  • ISBN 10 : 9783642021121
  • Total Read : 89
  • File Size : 19,9 Mb

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Signal Transduction Pathways Mechanisms and Diseases Summary:

Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.

Cell Surface GRP78  a New Paradigm in Signal Transduction Biology Book

Cell Surface GRP78 a New Paradigm in Signal Transduction Biology


  • Author : Salvatore V. Pizzo
  • Publisher : Academic Press
  • Release Date : 2018-03-20
  • Genre: Science
  • Pages : 144
  • ISBN 10 : 9780128123522
  • Total Read : 78
  • File Size : 18,6 Mb

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Cell Surface GRP78 a New Paradigm in Signal Transduction Biology Summary:

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative

Cellular Signal Processing Book

Cellular Signal Processing


  • Author : Friedrich Marks
  • Publisher : Garland Science
  • Release Date : 2017-05-17
  • Genre: Medical
  • Pages : 982
  • ISBN 10 : 9781351677219
  • Total Read : 83
  • File Size : 8,6 Mb

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Cellular Signal Processing Summary:

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Calmodulin and Signal Transduction Book

Calmodulin and Signal Transduction


  • Author : Linda J. Van Eldik
  • Publisher : Gulf Professional Publishing
  • Release Date : 1998
  • Genre: Medical
  • Pages : 482
  • ISBN 10 : 9780127138602
  • Total Read : 64
  • File Size : 6,7 Mb

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Calmodulin and Signal Transduction Summary:

This book focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. Contents - L.J. Van Eldik and D.M. Watterson, 'Calmodulin and Calcium Signal Transduction - An Introduction'. M.R. Nelson and W.J. Chazin, 'Calmodulin as a Calcium Sensor'. T.J. Lukas, S. Mirzoeva, and D.M. Watterson, 'Calmodulin-Regulated Protein Kinases'. B.A. Perrino and T.R. Soderling, 'Biochemistry and Pharmacology of Calmodulin-Regulated Phosphatase Calcineurin'. W.K. Sonnenburg, G.A. Wayman, D.R. Storm, and J.A. Beavo, 'Cyclic Nucleotide Regulation by Calmodulin'. J. Hu and L.J. Van Eldik, 'Regulation of Nitric Oxide Synthase by Calmodulin'. N.M. Bonafe and J.R. Sellers, 'Calmodulin-Binding Proteins of the Cytoskeleton'. P.C. Brandt and T.C. Vanaman, 'Calmodulin and Ion Flux Regulation'. Subject Index.

Histidine Kinases in Signal Transduction Book

Histidine Kinases in Signal Transduction


  • Author : Masayori Inouye
  • Publisher : Elsevier
  • Release Date : 2002-11-13
  • Genre: Science
  • Pages : 520
  • ISBN 10 : 9780080534015
  • Total Read : 63
  • File Size : 9,7 Mb

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Histidine Kinases in Signal Transduction Summary:

Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool. The first comprehensive book on the roles of histidine kinases in cells 23 in-depth chapters written by leading experts in the field Describes the most recent advances in the field of signal transduction