Regenerative Nephrology Book

Regenerative Nephrology


  • Author : Michael S. Goligorsky
  • Publisher : Academic Press
  • Release Date : 2021-06-12
  • Genre: Science
  • Pages : 528
  • ISBN 10 : 9780128233191
  • Total Read : 86
  • File Size : 11,5 Mb

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Regenerative Nephrology Summary:

Since the publication of the first edition of this book in 2010, an explosion of spectacular discoveries in the field of regeneration has compelled the current revisit of the field of Regenerative Nephrology. This second edition features subjects as diverse as age and gender influencing regenerative processes; mechanisms and pathways of premature cell senescence affecting kidney regeneration; the ways intrinsic regenerative processes can become subverted by noxious stressors eventuating in disease progression; novel mechanistic and engineering efforts to recreate functional kidney or its component parts; cell reprogramming and reconditioning as emerging tools of future regenerative efforts; and effects of various biologicals on kidney regeneration. These newer additions to the armamentarium of Regenerative Medicine and Nephrology have become an integral part of the second edition of the book. Cutting-edge investigations are summarized by the constellation of the most experienced contributing authors coming together from around the world under the umbrella of the second edition. A significant expansion of section on induced pluripotent cells and trajectories of their differentiation. This will be followed by mechanisms and modalities of cell reprogramming for therapeutic purposes A new section on tissue engineering of the kidney of interest to nephrologists and urologists An entire section dedicated to causes of regenerative failure with the emphasis on recent discoveries of senescent cells in kidney disease, pathologic effects of senescent cells, advents in senotherapies and rejuvenation therapies A vastly expanded section on pharmacotherapies promoting kidney regeneration, trials of engineered organs, manufacturing in regenerative medicine and smooth transition to the clinical trials, with an update on some ethical issues

Kidney Development  Disease  Repair and Regeneration Book

Kidney Development Disease Repair and Regeneration


  • Author : Melissa Helen Little
  • Publisher : Academic Press
  • Release Date : 2015-08-06
  • Genre: Medical
  • Pages : 614
  • ISBN 10 : 9780128004388
  • Total Read : 79
  • File Size : 6,8 Mb

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Kidney Development Disease Repair and Regeneration Summary:

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney’s inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Acute Kidney Injury and Regenerative Medicine Book

Acute Kidney Injury and Regenerative Medicine


  • Author : Yoshio Terada
  • Publisher : Springer Nature
  • Release Date : 2020-05-14
  • Genre: Medical
  • Pages : 396
  • ISBN 10 : 9789811511080
  • Total Read : 61
  • File Size : 13,9 Mb

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Acute Kidney Injury and Regenerative Medicine Summary:

This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Exploring the State of the Science in the Field of Regenerative Medicine Book

Exploring the State of the Science in the Field of Regenerative Medicine


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2017-06-16
  • Genre: Medical
  • Pages : 136
  • ISBN 10 : 9780309455114
  • Total Read : 65
  • File Size : 7,8 Mb

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Exploring the State of the Science in the Field of Regenerative Medicine Summary:

Regenerative medicine holds the potential to create living, functional cells and tissues that can be used to repair or replace those that have suffered potentially irreparable damage due to disease, age, traumatic injury, or genetic and congenital defects. The field of regenerative medicine is broad and includes research and development components of gene and cell therapies, tissue engineering, and non-biologic constructs. Although regenerative medicine has the potential to improve health and deliver economic benefits, this relatively new field faces challenges to developing policies and procedures to support the development of novel therapies are both safe and effective. In October 2016, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop with the goal of developing a broad understanding of the opportunities and challenges associated with regenerative medicine cellular therapies and related technologies. Participants explored the state of the science of cell-based regenerative therapies within the larger context of patient care and policy. This publication summarizes the presentations and discussions from the workshop.

Kidney Transplantation  Bioengineering  and Regeneration Book

Kidney Transplantation Bioengineering and Regeneration


  • Author : Giuseppe Orlando
  • Publisher : Academic Press
  • Release Date : 2017-06-08
  • Genre: Science
  • Pages : 1252
  • ISBN 10 : 9780128018361
  • Total Read : 98
  • File Size : 7,6 Mb

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Kidney Transplantation Bioengineering and Regeneration Summary:

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Organ Repair and Regeneration Book

Organ Repair and Regeneration


  • Author : Giuseppe Orlando
  • Publisher : Academic Press
  • Release Date : 2021-01-14
  • Genre: Science
  • Pages : 306
  • ISBN 10 : 9780128194522
  • Total Read : 72
  • File Size : 11,8 Mb

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Organ Repair and Regeneration Summary:

Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation. Covers all aspects of organ preservation, repair and regeneration Addresses the repair of organs that experience an Ischemia/Reperfusion (I/R) injury, those that are intended for transplantation, and specific issues related to each organ Presented by editors and authors who are physicians, surgeons and researchers in the field of organ transplantation and regenerative medicine

Tissue Engineering for Artificial Organs Book

Tissue Engineering for Artificial Organs


  • Author : Anwarul Hasan
  • Publisher : John Wiley & Sons
  • Release Date : 2017-03-28
  • Genre: Science
  • Pages : 754
  • ISBN 10 : 9783527689941
  • Total Read : 72
  • File Size : 8,7 Mb

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Tissue Engineering for Artificial Organs Summary:

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Comprehensive Nephrology Nursing Book

Comprehensive Nephrology Nursing


  • Author : Cleo J. Richard
  • Publisher : Unknown
  • Release Date : 1986
  • Genre: Kidneys
  • Pages : 529
  • ISBN 10 : UOM:39015012540137
  • Total Read : 59
  • File Size : 10,8 Mb

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Comprehensive Nephrology Nursing Summary: