Physical Models of Living Systems Book

Physical Models of Living Systems


  • Author : Philip Nelson
  • Publisher : WH Freeman
  • File Size : 15,5 Mb
  • Release Date : 2014-12-20
  • Genre: Science
  • Pages : 0
  • ISBN 10 : 1464140294

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This textbook helps students develop many of the competencies that form the basis of the MCAT2015. The only prerequisite for this is first-year physics. With the more advanced "Track-2" sections at the end of each chapter, the book can be used in graduate-level courses as well. Written for intermediate-level undergraduates pursuing any science or engineering major, Physical Models of Living Systems, gives students the research skills they require but are often left unaddressed in traditional courses. Skills such as basic modeling, probabilistic modeling and data analysis methods. All of these basic skills, which are relevant to nearly any field of science or engineering, are presented in the context of case studies from living systems. This living systems include virus dynamics, bacterial genetics, statistical inference and synthetic biology.

Models of Life Book

Models of Life


  • Author : Kim Sneppen
  • Publisher : Cambridge University Press
  • File Size : 15,5 Mb
  • Release Date : 2014-10-02
  • Genre: Science
  • Pages : 353
  • ISBN 10 : 9781107061903

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An overview of current models of biological systems, reflecting the major advances that have been made over the past decade.

Biophysics Book

Biophysics


  • Author : William Bialek
  • Publisher : Princeton University Press
  • File Size : 10,6 Mb
  • Release Date : 2012-12-17
  • Genre: Science
  • Pages : 640
  • ISBN 10 : 9781400845576

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Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology--from the discovery of DNA's structure to imaging of the human brain--have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles--the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes Instructor's manual (available only to teachers)

A Student s Guide to Python for Physical Modeling Book
Score: 4
From 1 Ratings

A Student s Guide to Python for Physical Modeling


  • Author : Jesse M. Kinder
  • Publisher : Princeton University Press
  • File Size : 17,7 Mb
  • Release Date : 2018-01-30
  • Genre: Computers
  • Pages : 168
  • ISBN 10 : 9780691180571

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A fully updated tutorial on the basics of the Python programming language for science students Python is a computer programming language that is rapidly gaining popularity throughout the sciences. This fully updated edition of A Student's Guide to Python for Physical Modeling aims to help you, the student, teach yourself enough of the Python programming language to get started with physical modeling. You will learn how to install an open-source Python programming environment and use it to accomplish many common scientific computing tasks: importing, exporting, and visualizing data; numerical analysis; and simulation. No prior programming experience is assumed. This tutorial focuses on fundamentals and introduces a wide range of useful techniques, including: Basic Python programming and scripting Numerical arrays Two- and three-dimensional graphics Monte Carlo simulations Numerical methods, including solving ordinary differential equations Image processing Animation Numerous code samples and exercises--with solutions—illustrate new ideas as they are introduced. Web-based resources also accompany this guide and include code samples, data sets, and more. This current edition brings the discussion of the Python language, Spyder development environment, and Anaconda distribution up to date. In addition, a new appendix introduces Jupyter notebooks.

Random Walks in Biology Book
Score: 5
From 1 Ratings

Random Walks in Biology


  • Author : Howard C. Berg
  • Publisher : Princeton University Press
  • File Size : 7,8 Mb
  • Release Date : 2018-11-20
  • Genre: Science
  • Pages : 168
  • ISBN 10 : 9781400820023

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This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know. It provides a sound basis for understanding random motions of molecules, subcellular particles, or cells, or of processes that depend on such motion or are markedly affected by it. Readers do not need to understand thermodynamics in order to acquire a knowledge of the physics involved in diffusion, sedimentation, electrophoresis, chromatography, and cell motility--subjects that become lively and immediate when the author discusses them in terms of random walks of individual particles.

Modeling Life Book
Score: 4.5
From 2 Ratings

Modeling Life


  • Author : Alan Garfinkel
  • Publisher : Springer
  • File Size : 17,6 Mb
  • Release Date : 2017-09-06
  • Genre: Mathematics
  • Pages : 445
  • ISBN 10 : 9783319597317

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This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

From Photon to Neuron Book

From Photon to Neuron


  • Author : Philip Charles Nelson
  • Publisher : Unknown
  • File Size : 6,6 Mb
  • Release Date : 2017
  • Genre: Light
  • Pages : 0
  • ISBN 10 : 0691175187

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What is light? -- Photons and life -- Color vision -- How photons know where to go -- Optical phenomena and life -- Direct image formation -- Imaging as inference -- Imaging by X-ray diffraction -- Vision in dim light -- The mechanism of visual transduction -- The first synapse and beyond -- Electrons, photons, and the Feynman principle -- Field quantization, polarization, and the orientation of a single molecule -- Quantum-mechanical theory of FRET

The Physics of Living Systems Book

The Physics of Living Systems


  • Author : Fabrizio Cleri
  • Publisher : Springer
  • File Size : 19,6 Mb
  • Release Date : 2016-10-08
  • Genre: Science
  • Pages : 620
  • ISBN 10 : 9783319306476

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In this book, physics in its many aspects (thermodynamics, mechanics, electricity, fluid dynamics) is the guiding light on a fascinating journey through biological systems, providing ideas, examples and stimulating reflections for undergraduate physics, chemistry and life-science students, as well as for anyone interested in the frontiers between physics and biology. Rather than introducing a lot of new information, it encourages young students to use their recently acquired knowledge to start seeing the physics behind the biology. As an undergraduate textbook in introductory biophysics, it includes the necessary background and tools, including exercises and appendices, to form a progressive course. In this case, the chapters can be used in the order proposed, possibly split between two semesters. The book is also an absorbing read for researchers in the life sciences who wish to refresh or go deeper into the physics concepts gleaned in their early years of scientific training. Less physics-oriented readers might want to skip the first chapter, as well as all the "gray boxes" containing the more formal developments, and create their own á-la-carte menu of chapters.

Evolutionary Dynamics Book
Score: 4
From 1 Ratings

Evolutionary Dynamics


  • Author : Martin A. Nowak
  • Publisher : Harvard University Press
  • File Size : 9,8 Mb
  • Release Date : 2006-09-29
  • Genre: Science
  • Pages : 384
  • ISBN 10 : 9780674417748

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At a time of unprecedented expansion in the life sciences, evolution is the one theory that transcends all of biology. Any observation of a living system must ultimately be interpreted in the context of its evolution. Evolutionary change is the consequence of mutation and natural selection, which are two concepts that can be described by mathematical equations. Evolutionary Dynamics is concerned with these equations of life. In this book, Martin A. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His work introduces readers to the powerful yet simple laws that govern the evolution of living systems, no matter how complicated they might seem. Evolution has become a mathematical theory, Nowak suggests, and any idea of an evolutionary process or mechanism should be studied in the context of the mathematical equations of evolutionary dynamics. His book presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos. Nowak then shows how evolutionary dynamics applies to critical real-world problems, including the progression of viral diseases such as AIDS, the virulence of infectious agents, the unpredictable mutations that lead to cancer, the evolution of altruism, and even the evolution of human language. His book makes a clear and compelling case for understanding every living system—and everything that arises as a consequence of living systems—in terms of evolutionary dynamics.

Physical Biology of the Cell Book

Physical Biology of the Cell


  • Author : Rob Phillips
  • Publisher : Garland Science
  • File Size : 16,5 Mb
  • Release Date : 2012-10-29
  • Genre: Science
  • Pages : 1089
  • ISBN 10 : 9781134111589

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Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that

Physical Models of Living Systems Book

Physical Models of Living Systems


  • Author : Philip Nelson
  • Publisher : Chiliagon Science
  • File Size : 10,6 Mb
  • Release Date : 2021-11-14
  • Genre: Science
  • Pages : 492
  • ISBN 10 : 173754024X

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Award-winning prof brings you from first-year classes to the frontiers of systems and synthetic biology, epidemic modeling, and imaging. Physical Models of Living Systems first develops the frameworks needed to understand modern ideas about inference from data, as they relate to biological physics research. Later chapters develop stochastic simulation as a tool to handle more complex systems, and then dynamical systems theory applied to cellular control networks, both natural and synthetic. Along the way, you'll also see the foundations of revolutionary advances in imaging (superresolution and cryo-electron microscopy), along with epidemic modeling, mechanobiology, excitable media, and more. The text also has significant overlap with competencies covered in the MCAT exam. Dozens of problems at all levels, many of them new in this edition, will help you to gain simulation and data visualization skills useful in any branch of quantitative science research.

Ocular Fluid Dynamics Book

Ocular Fluid Dynamics


  • Author : Giovanna Guidoboni
  • Publisher : Springer Nature
  • File Size : 8,8 Mb
  • Release Date : 2019-11-25
  • Genre: Mathematics
  • Pages : 612
  • ISBN 10 : 9783030258863

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The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature. Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

Research at the Intersection of the Physical and Life Sciences Book

Research at the Intersection of the Physical and Life Sciences


  • Author : National Research Council
  • Publisher : National Academies Press
  • File Size : 16,9 Mb
  • Release Date : 2010-03-25
  • Genre: Science
  • Pages : 122
  • ISBN 10 : 9780309147514

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Traditionally, the natural sciences have been divided into two branches: the biological sciences and the physical sciences. Today, an increasing number of scientists are addressing problems lying at the intersection of the two. These problems are most often biological in nature, but examining them through the lens of the physical sciences can yield exciting results and opportunities. For example, one area producing effective cross-discipline research opportunities centers on the dynamics of systems. Equilibrium, multistability, and stochastic behavior-concepts familiar to physicists and chemists-are now being used to tackle issues associated with living systems such as adaptation, feedback, and emergent behavior. Research at the Intersection of the Physical and Life Sciences discusses how some of the most important scientific and societal challenges can be addressed, at least in part, by collaborative research that lies at the intersection of traditional disciplines, including biology, chemistry, and physics. This book describes how some of the mysteries of the biological world are being addressed using tools and techniques developed in the physical sciences, and identifies five areas of potentially transformative research. Work in these areas would have significant impact in both research and society at large by expanding our understanding of the physical world and by revealing new opportunities for advancing public health, technology, and stewardship of the environment. This book recommends several ways to accelerate such cross-discipline research. Many of these recommendations are directed toward those administering the faculties and resources of our great research institutions-and the stewards of our research funders, making this book an excellent resource for academic and research institutions, scientists, universities, and federal and private funding agencies.

Computational Modeling in Biomedical Engineering and Medical Physics Book

Computational Modeling in Biomedical Engineering and Medical Physics


  • Author : Alexandru Morega
  • Publisher : Academic Press
  • File Size : 11,8 Mb
  • Release Date : 2020-09-15
  • Genre: Science
  • Pages : 314
  • ISBN 10 : 9780128178980

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Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies. Presents the fundamentals of mathematical and numerical modeling of engineering problems in medicine Discusses many of the most common modelling scenarios for Biomedical Engineering, including, electrical activity of the heart hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave h

Self Organized Criticality Book

Self Organized Criticality


  • Author : Henrik Jeldtoft Jensen
  • Publisher : Cambridge University Press
  • File Size : 16,9 Mb
  • Release Date : 1998
  • Genre: Science
  • Pages : 172
  • ISBN 10 : 0521483719

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A clear and concise introduction to this new, cross-disciplinary field.