Personalized and Precision Medicine Informatics Book

Personalized and Precision Medicine Informatics

  • Author : Terrence Adam
  • Publisher : Springer Nature
  • File Size : 10,9 Mb
  • Release Date : 2019-09-17
  • Genre: Medical
  • Pages : 349
  • ISBN 10 : 9783030186265


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This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.

Digital Personalized Health and Medicine Book

Digital Personalized Health and Medicine

  • Author : L.B. Pape-Haugaard
  • Publisher : IOS Press
  • File Size : 6,7 Mb
  • Release Date : 2020-06-17
  • Genre: Medical
  • Pages : 1498
  • ISBN 10 : 9781643680835


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Digital health and medical informatics have grown in importance in recent years, and have now become central to the provision of effective healthcare around the world. This book presents the proceedings of the 30th Medical Informatics Europe conference (MIE). This edition of the conference, hosted by the European Federation for Medical Informatics (EFMI) since the 1970s, was due to be held in Geneva, Switzerland in April 2020, but as a result of measures to prevent the spread of the Covid19 pandemic, the conference itself had to be cancelled. Nevertheless, because this collection of papers offers a wealth of knowledge and experience across the full spectrum of digital health and medicine, it was decided to publish the submissions accepted in the review process and confirmed by the Scientific Program Committee for publication, and these are published here as planned. The 232 papers are themed under 6 section headings: biomedical data, tools and methods; supporting care delivery; health and prevention; precision medicine and public health; human factors and citizen centered digital health; and ethics, legal and societal aspects. A 7th section deals with the Swiss personalized health network, and section 8 includes the 125 posters accepted for the conference. Offering an overview of current trends and developments in digital health and medical informatics, the book provides a valuable information resource for researchers and health practitioners alike.

Toward Precision Medicine Book

Toward Precision Medicine

  • Author : National Research Council
  • Publisher : National Academies Press
  • File Size : 19,8 Mb
  • Release Date : 2012-01-16
  • Genre: Medical
  • Pages : 142
  • ISBN 10 : 9780309222228


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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Progress and Challenges in Precision Medicine Book

Progress and Challenges in Precision Medicine

  • Author : Mukesh Verma
  • Publisher : Academic Press
  • File Size : 15,5 Mb
  • Release Date : 2016-12-22
  • Genre: Medical
  • Pages : 344
  • ISBN 10 : 9780128095027


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Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

MEDINFO 2017  Precision Healthcare Through Informatics Book

MEDINFO 2017 Precision Healthcare Through Informatics

  • Author : A.V. Gundlapalli
  • Publisher : IOS Press
  • File Size : 18,8 Mb
  • Release Date : 2018-01-31
  • Genre: Medical
  • Pages : 1440
  • ISBN 10 : 9781614998303


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Medical informatics is a field which continues to evolve with developments and improvements in foundational methods, applications, and technology, constantly offering opportunities for supporting the customization of healthcare to individual patients. This book presents the proceedings of the 16th World Congress of Medical and Health Informatics (MedInfo2017), held in Hangzhou, China, in August 2017, which also marked the 50th anniversary of the International Medical Informatics Association (IMIA). The central theme of MedInfo2017 was "Precision Healthcare through Informatics", and the scientific program was divided into five tracks: connected and digital health; human data science; human, organizational, and social aspects; knowledge management and quality; and safety and patient outcomes. The 249 accepted papers and 168 posters included here span the breadth and depth of sub-disciplines in biomedical and health informatics, such as clinical informatics; nursing informatics; consumer health informatics; public health informatics; human factors in healthcare; bioinformatics; translational informatics; quality and safety; research at the intersection of biomedical and health informatics; and precision medicine. The book will be of interest to all those who wish to keep pace with advances in the science, education, and practice of biomedical and health informatics worldwide.

Mental Health Informatics Book

Mental Health Informatics

  • Author : Jessica D. Tenenbaum
  • Publisher : Springer Nature
  • File Size : 9,6 Mb
  • Release Date : 2021-11-18
  • Genre: Medical
  • Pages : 534
  • ISBN 10 : 9783030705589


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This textbook provides a detailed resource introducing the subdiscipline of mental health informatics. It systematically reviews the methods, paradigms, tools and knowledge base in both clinical and bioinformatics and across the spectrum from research to clinical care. Key foundational technologies, such as terminologies, ontologies and data exchange standards are presented and given context within the complex landscape of mental health conditions, research and care. The learning health system model is utilized to emphasize the bi-directional nature of the translational science associated with mental health processes. Descriptions of the data, technologies, paradigms and products that are generated by and used in each process and their limitations are discussed. Mental Health Informatics: Enabling a Learning Mental Healthcare System is a comprehensive introductory resource for students, educators and researchers in mental health informatics and related behavioral sciences. It is an ideal resource for use in a survey course for both pre- and post-doctoral training programs, as well as for healthcare administrators, funding entities, vendors and product developers working to make mental healthcare more evidence-based.

Precision Medicine Powered by pHealth and Connected Health Book

Precision Medicine Powered by pHealth and Connected Health

  • Author : Nicos Maglaveras
  • Publisher : Springer
  • File Size : 5,8 Mb
  • Release Date : 2017-11-16
  • Genre: Technology & Engineering
  • Pages : 269
  • ISBN 10 : 9789811074196


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This volume presents the proceedings of the 3rd ICBHI which took place in Thessaloniki on 18-21 November, 2017.The area of biomedical and health informatics is exploding at all scales. The developments in the areas of medical devices, eHealth and personalized health as enabling factors for the evolution of precision medicine are quickly developing and demand the development of new scaling tools, integration frameworks and methodologies.

Biomedical Informatics Book
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Biomedical Informatics

  • Author : Edward H. Shortliffe
  • Publisher : Springer Science & Business Media
  • File Size : 10,7 Mb
  • Release Date : 2013-12-02
  • Genre: Medical
  • Pages : 965
  • ISBN 10 : 9781447144748


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The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Health Informatics Data Analysis Book

Health Informatics Data Analysis

  • Author : Dong Xu
  • Publisher : Springer
  • File Size : 13,9 Mb
  • Release Date : 2017-09-08
  • Genre: Medical
  • Pages : 210
  • ISBN 10 : 9783319449814


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This book provides a comprehensive overview of different biomedical data types, including both clinical and genomic data. Thorough explanations enable readers to explore key topics ranging from electrocardiograms to Big Data health mining and EEG analysis techniques. Each chapter offers a summary of the field and a sample analysis. Also covered are telehealth infrastructure, healthcare information association rules, methods for mass spectrometry imaging, environmental biodiversity, and the global nonlinear fitness function for protein structures. Diseases are addressed in chapters on functional annotation of lncRNAs in human disease, metabolomics characterization of human diseases, disease risk factors using SNP data and Bayesian methods, and imaging informatics for diagnostic imaging marker selection. With the exploding accumulation of Electronic Health Records (EHRs), there is an urgent need for computer-aided analysis of heterogeneous biomedical datasets. Biomedical data is notorious for its diversified scales, dimensions, and volumes, and requires interdisciplinary technologies for visual illustration and digital characterization. Various computer programs and servers have been developed for these purposes by both theoreticians and engineers. This book is an essential reference for investigating the tools available for analyzing heterogeneous biomedical data. It is designed for professionals, researchers, and practitioners in biomedical engineering, diagnostics, medical electronics, and related industries.

Handbook of Biomarkers and Precision Medicine Book

Handbook of Biomarkers and Precision Medicine

  • Author : Claudio Carini
  • Publisher : CRC Press
  • File Size : 11,7 Mb
  • Release Date : 2019-04-16
  • Genre: Mathematics
  • Pages : 1025
  • ISBN 10 : 9780429574627


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"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features: Detailed insights into biomarker discovery, validation and diagnostic development with implementation strategies Lessons-learned from successful Precision Medicine case studies A variety of exciting and emerging biomarker technologies The next frontiers and future challenges of biomarkers in Precision Medicine Claudio Carini, Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU, USA and Asia. Currently, Dr. Carini is Honorary Faculty at Kings’s College School of Medicine, London, UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca, Cambridge, UK. Prof.dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school, Nijmegen, NL.

Precision Medicine and Artificial Intelligence Book

Precision Medicine and Artificial Intelligence

  • Author : Michael Mahler
  • Publisher : Academic Press
  • File Size : 11,6 Mb
  • Release Date : 2021-03-12
  • Genre: Science
  • Pages : 300
  • ISBN 10 : 9780323854320


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Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

P5 eHealth  An Agenda for the Health Technologies of the Future Book

P5 eHealth An Agenda for the Health Technologies of the Future

  • Author : Gabriella Pravettoni
  • Publisher : Springer Nature
  • File Size : 18,7 Mb
  • Release Date : 2019-11-29
  • Genre: Psychology
  • Pages : 191
  • ISBN 10 : 9783030279943


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This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.

Integrating Information Technology and Management for Quality of Care Book

Integrating Information Technology and Management for Quality of Care

  • Author : J. Mantas
  • Publisher : IOS Press
  • File Size : 14,5 Mb
  • Release Date : 2014-07-24
  • Genre: Medical
  • Pages : 344
  • ISBN 10 : 9781614994237


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The impact of information technology on the management of healthcare has been enormous in recent years, and it continues to grow in scope and complexity. This book presents papers from the 2014 International Conference on Informatics, Management, and Technology in Healthcare (ICIMTH), held in Athens, Greece, in July 2014. The book includes 79 full papers and 12 poster presentations as well as keynotes, two workshops and three tutorials. Papers are divided into sections including: clinical informatics; decision support and intelligent systems; e-learning and education; health informatics, information management and technology assessment; healthcare IT; mobile technology in healthcare; public health informatics and issues; social and legal issues; and telemedicine. The book will be of interest to all those whose work involves the use of biomedical and health informatics.

Can precision medicine be personal  can personalized medicine be  Book

Can precision medicine be personal can personalized medicine be

  • Author : Y. Michael Barilan
  • Publisher : Oxford University Press
  • File Size : 16,9 Mb
  • Release Date : 2022-02-10
  • Genre: Medical
  • Pages : 336
  • ISBN 10 : 9780192608680


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People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.

Essentials of Genomic and Personalized Medicine Book

Essentials of Genomic and Personalized Medicine

  • Author : Geoffrey S. Ginsburg
  • Publisher : Academic Press
  • File Size : 14,6 Mb
  • Release Date : 2009-10-02
  • Genre: Science
  • Pages : 850
  • ISBN 10 : 0080958117


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Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science