Neuronal Chloride Transporters in Health and Disease
- Author : Xin Tang
- Publisher : Academic Press
- Release Date : 2020-06
- Genre: Medical
- Pages : 650
- ISBN 10 : 0128153180
- Total Read : 81
- File Size : 13,8 Mb
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Neuronal Chloride Transporters in Health and Disease Summary:
Neuronal Chloride Transporters in Health and Disease introduces core concepts and recent advances surrounding the physiology and pathophysiology of neuronal chloride transporters, with particular focus on the KCC and NKCC families of proteins. Chloride transporter biology is reviewed, including its role in setting the transmembrane chloride gradient and in chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters also address post-translational modifications and the trafficking of chloride transporters, protein interaction partners, and the genetic and environmental factors that regulate expression in neurons. This new volume will provide readers with an up-to-date summary on recent advances in neuronal chloride transporter research, with a particular emphasis on key and emerging topics in the field.