Neural Stem Cells and Adult Neurogenesis Book

Neural Stem Cells and Adult Neurogenesis


  • Author : Arie S. Mobley
  • Publisher : Academic Press
  • Release Date : 2019-03-15
  • Genre: Science
  • Pages : 242
  • ISBN 10 : 9780128110140
  • Total Read : 94
  • File Size : 9,6 Mb

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Neural Stem Cells and Adult Neurogenesis Summary:

Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons' contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format. Provides a basic understanding of what a stem cell is, the different types, and their potential in health and research Details adult neurogenesis and its role in behavior, stroke and disease Includes walkthrough and technology boxes that illustrate experimental concepts, new approaches and techniques

Neural Stem Cells and Adult Neurogenesis Book

Neural Stem Cells and Adult Neurogenesis


  • Author : Arie S. Mobley
  • Publisher : Academic Press
  • Release Date : 2019-02-28
  • Genre: Science
  • Pages : 241
  • ISBN 10 : 9780128110157
  • Total Read : 93
  • File Size : 6,9 Mb

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Neural Stem Cells and Adult Neurogenesis Summary:

Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format. Provides a basic understanding of what a stem cell is, the different types, and their potential in health and research Details adult neurogenesis and its role in behavior, stroke and disease Includes walkthrough and technology boxes that illustrate experimental concepts, new approaches and techniques

Stem Cells and Regenerative Medicine Book

Stem Cells and Regenerative Medicine


  • Author : Philippe Taupin
  • Publisher : Nova Publishers
  • Release Date : 2008
  • Genre: Developmental neurobiology
  • Pages : 186
  • ISBN 10 : 1604564725
  • Total Read : 61
  • File Size : 8,9 Mb

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Stem Cells and Regenerative Medicine Summary:

The subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, fetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises adult neurogenesis and neural stem cell research and therapy.

Neural Stem Cells and Therapy Book

Neural Stem Cells and Therapy


  • Author : Tao Sun
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-02-15
  • Genre: Science
  • Pages : 456
  • ISBN 10 : 9789533079585
  • Total Read : 82
  • File Size : 12,9 Mb

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Neural Stem Cells and Therapy Summary:

This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.

Adult Neurogenesis and Neural Stem Cells in Mammals Book

Adult Neurogenesis and Neural Stem Cells in Mammals


  • Author : Philippe Taupin
  • Publisher : Nova Publishers
  • Release Date : 2006
  • Genre: Medical
  • Pages : 222
  • ISBN 10 : 1594548560
  • Total Read : 76
  • File Size : 5,6 Mb

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Adult Neurogenesis and Neural Stem Cells in Mammals Summary:

This title contains a book and CD. The brain has a number of nerve cells estimated at a magnitude of 10 to 100 billion, and 1014 to 1015 synapses, and therefore is the most complex organ of the human body. During fetal development the foundations of the brain are laid as billions of neurons form appropriate connections and patterns. In the adult mammalian brain, most neurons are post-mitotic, and therefore at risk for irreversible damage. As we age, atrophy of the brain occurs. As brain weight declines the volume of the brain in the 8th decade is reduced by 6 per cent -10 per cent versus the third decade, and neuronal loss occurs, up to 10,000 to 100,000 neurons are lost per day, though this estimation is being revised downward with the advance of more sophisticated measurements.

Adult neurogenesis twenty years later  physiological function versus brain repair Book

Adult neurogenesis twenty years later physiological function versus brain repair


  • Author : Paolo Peretto
  • Publisher : Frontiers Media SA
  • Release Date : 2015-05-01
  • Genre: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Pages : 121
  • ISBN 10 : 9782889194940
  • Total Read : 85
  • File Size : 12,5 Mb

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Adult neurogenesis twenty years later physiological function versus brain repair Summary:

The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity. On a theoretical basis, this achievement opened new perspectives for therapeutic approaches in restorative and regenerative neurology. Nevertheless, in spite of striking advancement concerning the molecular and cellular mechanisms which allow and regulate the neurogenic process, its exploitation in mammals for brain repair strategies remains unsolved. In non-mammalian vertebrates, adult neurogenesis also contributes to brain repair/regeneration. In mammals, neural stem cells do respond to pathological conditions in the so called "reactive neurogenesis", yet without substantial regenerative outcome. Why, even in the presence of stem cells in the brain, we lack an effective reparative outcome in terms of regenerative neurology, and which factors hamper the attainment of this goal? Essentially, what remains unanswered is the question whether (and how) physiological functions of adult neurogenesis in mammals can be exploited for brain repair purposes.

Adult Neurogenesis Book
Score: 5
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Adult Neurogenesis


  • Author : Fred Gage
  • Publisher : CSHL Press
  • Release Date : 2008
  • Genre: Medical
  • Pages : 667
  • ISBN 10 : 9780879697846
  • Total Read : 98
  • File Size : 11,7 Mb

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Adult Neurogenesis Summary:

The idea that the adult brain of mammals can generate new neurons has only recently been accepted by the scientific community, and research in this exciting area is now in full swing. Bringing together leading researchers in the field of adult neurogenesis, the 30 chapters in this monograph provide a valuable overview of this emerging field and lay the groundwork for future studies. Adult Neurogenesis includes discussions on neural stem cell biology; methods and models for studying adult neurogenesis; physiological and molecular processes and their control; related neurological diseases; and comparisons of neurogenesis in humans, birds, fish, and invertebrates. It will be of interest to all researchers in neurobiology as well as those in the medical field, as it has implications for understanding depression, epilepsy, and other psychiatric disorders.

The ventricular subventricular zone  a source of oligodendrocytes in the adult brain Book

The ventricular subventricular zone a source of oligodendrocytes in the adult brain


  • Author : Oscar Gonzalez-Perez
  • Publisher : Frontiers E-books
  • Release Date : 2014-09-30
  • Genre: Brain
  • Pages : 251
  • ISBN 10 : 9782889192687
  • Total Read : 96
  • File Size : 16,5 Mb

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The ventricular subventricular zone a source of oligodendrocytes in the adult brain Summary:

Demyelinating diseases are characterized by an extensive loss of oligodendrocytes and myelin sheaths from axolemma, which commonly result in disability in young adults. To date, there is no effective treatment against these neurological disorders. In the adult brain, there are neural stem cells (NSCs) that reside within a niche denominated ventricular-subventricular zone (V-SVZ) in the lateral wall of the cerebral ventricles. NSCs give rise to neurons and oligodendrocytes that help preserve cellular homeostasis. Growing evidence indicates that V-SVZ progenitor cells may represent an endogenous source of oligodendrocytes that can be useful to treat demyelinating diseases. This e-Book “The ventricular-subventricular zone as a source of oligodendrocytes in the adult brain” collected the most recent evidence regarding the mechanisms that modulate the proliferation, migration, quiescence, cell-fate choices and survival of oligodendrocyte precursors generated in the V-SVZ. Herein, we compiled information about the role of Sonic hedgehog, NMDA receptors, ErbB proteins, hemopressin, erythropoietin, osmolarity and microglia in the oligodendrocyte production. Some chapters also describe the role of oligodendrocyte precursors in the preservation of cellular homeostasis, aging and white matter repair. All these information is presented as novel research findings, short communications, and review articles, which were written by experts in the field of oligodendrocyte generation, myelin production and white matter re-myelination.