Molecular Biology Of Assemblies And Machines

Molecular Biology of Assemblies and Machines

• Author : Alasdair Steven
• Publisher : Garland Science
• File Size : 6,7 Mb
• Release Date : 2016-02-18
• Genre: Medical
• Pages : 880
• ISBN 10 : 9781000064902

Download Molecular Biology of Assemblies and Machines Book in PDF and ePub

Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology,

Molecular Biology of Assemblies and Machines

• Author : Alasdair C. Steven
• Publisher : Garland Science
• File Size : 13,5 Mb
• Release Date : 2016-02-18
• Genre: Science
• Pages : 888
• ISBN 10 : 9781134982820

Download Molecular Biology of Assemblies and Machines Book in PDF and ePub

Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine. Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.

Life s Ratchet

• Author : Peter M Hoffmann
• Publisher : Basic Books
• File Size : 15,9 Mb
• Release Date : 2012-10-30
• Genre: Science
• Pages : 288
• ISBN 10 : 9780465033362

Download Life s Ratchet Book in PDF and ePub

Life is an enduring mystery. Yet, science tells us that living beings are merely sophisticated structures of lifeless molecules. If this view is correct, where do the seemingly purposeful motions of cells and organisms originate? In Life's Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. Below the calm, ordered exterior of a living organism lies microscopic chaos, or what Hoffmann calls the molecular storm -- specialized molecules immersed in a whirlwind of colliding water molecules. Our cells are filled with molecular machines, which, like tiny ratchets, transform random motion into ordered activity, and create the "purpose" that is the hallmark of life. Tiny electrical motors turn electrical voltage into motion, nanoscale factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. The cell is like a city -- an unfathomable, complex collection of molecular workers working together to create something greater than themselves. Life, Hoffman argues, emerges from the random motions of atoms filtered through these sophisticated structures of our evolved machinery. We are agglomerations of interacting nanoscale machines more amazing than anything in science fiction. Rather than relying on some mysterious "life force" to drive them -- as people believed for centuries -- life's ratchets harness instead the second law of thermodynamics and the disorder of the molecular storm. Grounded in Hoffmann's own cutting-edge research, Life's Ratchet reveals the incredible findings of modern nanotechnology to tell the story of how the noisy world of atoms gives rise to life itself.

Molecular Biology of the Cell

• Author : Bruce Alberts
• Publisher : Unknown
• File Size : 15,9 Mb
• Release Date : 2004
• Genre: Cells
• Pages : 0
• ISBN 10 : 0815332181

Download Molecular Biology of the Cell Book in PDF and ePub

Protein Physics

• Author : Alexei V. Finkelstein
• Publisher : Elsevier
• File Size : 5,8 Mb
• Release Date : 2016-06-22
• Genre: Science
• Pages : 528
• ISBN 10 : 9780081012369

Download Protein Physics Book in PDF and ePub

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry. Fully revised and expanded new edition based on the latest research developments in protein physics Written by the world's top expert in the field Deals with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states Summarizes, in a systematic form, the results of several decades of worldwide fundamental research on protein physics and their structure and folding Examines experimental data on protein structure in the post-genome era

Protein NMR

• Author : Ranajeet Ghose
• Publisher : Unknown
• File Size : 20,7 Mb
• Release Date : 2018
• Genre: Medicine
• Pages : 446
• ISBN 10 : 149397386X

Download Protein NMR Book in PDF and ePub

This volume covers state-of-the-art applications of solid-state and solution nuclear magnetic resonance( NMR) spectroscopy to study protein structure, dynamics and interactions. Chapters detail various aspects of data acquisition and processing, determination of the structure, multi-timescale dynamics of entities ranging from individual proteins to large macromolecular complexes to intact viral assemblies. The final two chapters will highlight the promise of NMR beyond field strengths of 1 GHz to study the structure, dynamics and interactions of a larger class of proteins and protein complexes of extraordinary biological interest. Written in the highly successful Methods in Molecular Biology series format, chapters provide detailed laboratory protocols and troubleshooting tips that would be of great practical help to NMR spectroscopists with different levels of expertise.

Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology

• Author : Kumar Selvarajoo
• Publisher : Springer Nature
• File Size : 17,9 Mb
• Release Date : 2022-10-13
• Genre: Science
• Pages : 457
• ISBN 10 : 9781071626177

Download Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology Book in PDF and ePub

This volume provides protocols for computational, statistical, and machine learning methods that are mainly applied to the study of metabolic engineering, synthetic biology, and disease applications. These techniques support the latest progress in cross-disciplinary research that integrates the different scales of biological complexity. The topics covered in this book are geared toward researchers with a background in engineering, computational analytical, and modeling experience and cover a broad range of topics in computational and machine learning approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology is a valuable resource for any researcher or scientist who wants to learn more about the latest computational methods and how they are applied toward the understanding and prediction of complex biology.

Molecular Biology

• Author : David P. Clark
• Publisher : Elsevier
• File Size : 11,8 Mb
• Release Date : 2009-10-21
• Genre: Science
• Pages : 784
• ISBN 10 : 9780123785909

Download Molecular Biology Book in PDF and ePub

Molecular Biology: Academic Cell Update provides an introduction to the fundamental concepts of molecular biology and its applications. It deliberately covers a broad range of topics to show that molecular biology is applicable to human medicine and health, as well as veterinary medicine, evolution, agriculture, and other areas. The present Update includes journal specific images and test bank. It also offers vocabulary flashcards. The book begins by defining some basic concepts in genetics such as biochemical pathways, phenotypes and genotypes, chromosomes, and alleles. It explains the characteristics of cells and organisms, DNA, RNA, and proteins. It also describes genetic processes such as transcription, recombination and repair, regulation, and mutations. The chapters on viruses and bacteria discuss their life cycle, diversity, reproduction, and gene transfer. Later chapters cover topics such as molecular evolution; the isolation, purification, detection, and hybridization of DNA; basic molecular cloning techniques; proteomics; and processes such as the polymerase chain reaction, DNA sequencing, and gene expression screening. Up to date description of genetic engineering, genomics, and related areas Basic concepts followed by more detailed, specific applications Hundreds of color illustrations enhance key topics and concepts Covers medical, agricultural, and social aspects of molecular biology Organized pedagogy includes running glossaries and keynotes (mini-summaries) to hasten comprehension

Philosophical Perspectives on the Engineering Approach in Biology

• Author : Sune Holm
• Publisher : Routledge
• File Size : 12,8 Mb
• Release Date : 2020-06-07
• Genre: Social Science
• Pages : 216
• ISBN 10 : 9781351212229

Download Philosophical Perspectives on the Engineering Approach in Biology Book in PDF and ePub

Philosophical Perspectives on the Engineering Approach in Biology provides a philosophical examination of what has been called the most powerful metaphor in biology: The machine metaphor. The chapters collected in this volume discuss the idea that living systems can be understood through the lens of engineering methods and machine metaphors from both historical, theoretical, and practical perspectives. In their contributions the authors examine questions about scientific explanation and methodology, the interrelationship between science and engineering, and the impact that the use of engineering metaphors in science may have for bioethics and science communication, such as the worry that its wide application reinforces public misconceptions of the nature of new biotechnology and biological life. The book also contains an introduction that describes the rise of the machine analogy and the many ways in which it plays a central role in fundamental debates about e.g. design, adaptation, and reductionism in the philosophy of biology. The book will be useful as a core reading for professionals as well as graduate and undergraduate students in courses of philosophy of science and for life scientists taking courses in philosophy of science and bioethics.

Molecular Machines in Biology

• Author : Joachim Frank
• Publisher : Cambridge University Press
• File Size : 10,9 Mb
• Release Date : 2011-12-19
• Genre: Science
• Pages : null
• ISBN 10 : 9781139499903

Download Molecular Machines in Biology Book in PDF and ePub

The concept of molecular machines in biology has transformed the medical field in a profound way. Many essential processes that occur in the cell, including transcription, translation, protein folding and protein degradation, are all carried out by molecular machines. This volume focuses on important molecular machines whose architecture is known and whose functional principles have been established by tools of biophysical imaging (X-ray crystallography and cryo-electron microscopy) and fluorescence probing (single-molecule FRET). This edited volume includes contributions from prominent scientists and researchers who understand and have explored the structure and functions of these machines. This book is essential for students and professionals in the medical field who want to learn more about molecular machines.

Above the Gene Beyond Biology

• Author : Jan Baedke
• Publisher : University of Pittsburgh Press
• File Size : 8,8 Mb
• Release Date : 2018-07-20
• Genre: Science
• Pages : 296
• ISBN 10 : 9780822983408

Download Above the Gene Beyond Biology Book in PDF and ePub

Epigenetics is currently one of the fastest-growing fields in the sciences. Epigenetic information not only controls DNA expression but links genetic factors with the environmental experiences that influence the traits and characteristics of an individual. What we eat, where we work, and how we live affects not only the activity of our genes but that of our offspring as well. This discovery has imposed a revolutionary theoretical shift on modern biology, especially on evolutionary theory. It has helped to uncover the developmental processes leading to cancer, obesity, schizophrenia, alcoholism, and aging, and to facilitate associated medial applications such as stem cell therapy and cloning. Above the Gene, Beyond Biology explores how biologists in this booming field investigate and explain living systems. Jan Baedke offers the first comprehensive philosophical discussion of epigenetic concepts, explanations, and methodologies so that we can better understand this “epigenetic turn” in the life sciences from a philosophical perspective.

Plenty of Room for Biology at the Bottom

• Author : Ehud Gazit
• Publisher : World Scientific
• File Size : 11,6 Mb
• Release Date : 2013
• Genre: Science
• Pages : 214
• ISBN 10 : 9781848169319

Download Plenty of Room for Biology at the Bottom Book in PDF and ePub

This expanded and updated edition of the 2007 version introduces readers from various backgrounds to the rapidly growing interface between biology and nanotechnology. It intellectually integrates concepts, applications, and outlooks from these major scientific fields and presents them to readers from diverse backgrounds in a comprehensive and didactic manner.Written by two leading nanobiologists actively involved at the forefront of the field both as researchers and educators, this book takes the reader from the fundamentals of nanobiology to the most advanced applications.The book fulfils a unique niche: to address not only students, but also scientists who are eager (and nowadays obliged) to learn about other state-of-the-art disciplines. The book is written in such a way as to be accessible to biologists, chemists, and physicists with no background in nanotechnology (for example biologists who are interested in inorganic nanostructures or physicists who would like to learn about biological assemblies and applications thereof). It is reader-friendly and will appeal to a wide audience not only in academia but also in the industry and anyone interested in learning more about nanobiotechnology.

The Biology of Belief 10th Anniversary Edition

• Author : Bruce H. Lipton
• Publisher : Hay House, Inc
• File Size : 15,5 Mb
• Release Date : 2016-10-11
• Genre: Body, Mind & Spirit
• Pages : 313
• ISBN 10 : 9781401952471

Download The Biology of Belief 10th Anniversary Edition Book in PDF and ePub

This 10th-anniversary edition of Bruce Lipton’s best-selling book The Biology of Belief has been updated to bolster the book’s central premise with the latest scientific discoveries—and there have been a lot in the last decade. The Biology of Belief is a groundbreaking work in the field of new biology. Former medical school professor and research scientist Bruce H. Lipton, Ph.D., presents his experiments, and those of other leading-edge scientists, which examine in great detail the mechanisms by which cells receive and process information. The implications of this research radically change our understanding of life, showing that genes and DNA do not control our biology; instead, DNA is controlled by signals from outside the cell, including the energetic messages emanating from our positive and negative thoughts. This profoundly hopeful synthesis of the latest and best research in cell biology and quantum physics has been hailed as a major breakthrough, showing that our bodies can be changed as we retrain our thinking.

The Biology of Belief 10th Anniversary Edition

• Author : Bruce H. Lipton, Ph.D.
• Publisher : Hay House, Inc
• File Size : 13,5 Mb
• Release Date : 2015-10-13
• Genre: Body, Mind & Spirit
• Pages : 264
• ISBN 10 : 9781401949594

Download The Biology of Belief 10th Anniversary Edition Book in PDF and ePub

Unleashing the power of consciousness, matter and miracles It has been ten years since the publication of The Biology of Belief, Bruce Lipton’s seminal book on the relationship between mind and body that changed the way we think about our lives, our health, and our planet. During that time, research in this field has grown exponentially – Lipton’s groundbreaking experiments have now been endorsed by more than a decade of rigorous scientific study. In this greatly expanded edition, Lipton, a former medical school professor and research scientist, explores his own experiments and those of other leading-edge scientists that have unraveled in ever greater detail how truly connected the mind, body, and spirit are. It is now widely recognized that genes and DNA do not control our biology. Instead, they are controlled by signals from outside the cell, including energetic messages emanating from our thoughts. This profoundly hopeful synthesis of the latest and best research in cell biology and quantum physics puts the power to create a healthy, joyous life back in our own hands. When we transform our conscious and subconscious thoughts, we transform our lives, and in the process help humanity evolve to a new level of understanding and peace.

Opportunities in Biology

• Author : National Research Council
• Publisher : National Academies
• File Size : 7,9 Mb
• Release Date : 1989-01-01
• Genre: Science
• Pages : 471
• ISBN 10 : 9780309039277

Download Opportunities in Biology Book in PDF and ePub

Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.