Microbial Metabolism and Disease Book

Microbial Metabolism and Disease


  • Author : Elena L. Paley
  • Publisher : Academic Press
  • Release Date : 2021-03-13
  • Genre: Science
  • Pages : 306
  • ISBN 10 : 9780323884464
  • Total Read : 66
  • File Size : 18,5 Mb

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Microbial Metabolism and Disease Summary:

Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer’s disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body. Explores microbial metabolic pathways in the human body and implications for disease Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways Considers a variety of diseases and disorders, such as Alzheimer’s disease, metabolic syndromes, Crohn’s disease and Covid-19 Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health

Metabolic Interaction in Infection Book

Metabolic Interaction in Infection


  • Author : Ricardo Silvestre
  • Publisher : Springer
  • Release Date : 2018-04-06
  • Genre: Science
  • Pages : 476
  • ISBN 10 : 9783319749327
  • Total Read : 60
  • File Size : 18,6 Mb

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Metabolic Interaction in Infection Summary:

This book focuses on host–pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.

The Human Microbiome  Diet  and Health Book

The Human Microbiome Diet and Health


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2013-03-13
  • Genre: Medical
  • Pages : 197
  • ISBN 10 : 9780309265850
  • Total Read : 62
  • File Size : 6,7 Mb

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The Human Microbiome Diet and Health Summary:

The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.

Reprogramming Microbial Metabolic Pathways Book

Reprogramming Microbial Metabolic Pathways


  • Author : Xiaoyuan Wang
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-10-20
  • Genre: Medical
  • Pages : 445
  • ISBN 10 : 9789400750548
  • Total Read : 83
  • File Size : 19,7 Mb

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Reprogramming Microbial Metabolic Pathways Summary:

Metabolic engineering has been developed over the past 20 years to become an important tool for rational engineering of microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of metabolites in microorganisms. The overall goal is to achieve a better understanding of metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production. This book brings together contributions from leading researchers at the cutting edge of these topics. The subject matter is divided into two sections. The first section deals with novel and emerging methods for redesigning microorganisms exploiting systems biology and gene regulation. The second discusses practical aspects of metabolic engineering for over production of a variety of valuable chemicals and materials by fermentation.

Metabolism and Bacterial Pathogenesis Book

Metabolism and Bacterial Pathogenesis


  • Author : Tyrrell Conway
  • Publisher : John Wiley & Sons
  • Release Date : 2015-09-01
  • Genre: Science
  • Pages : null
  • ISBN 10 : 9781683673347
  • Total Read : 85
  • File Size : 5,8 Mb

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Metabolism and Bacterial Pathogenesis Summary:

Groundbreaking thinking on how bacterial metabolism is foundational to pathogenesis For too long, bacterial metabolism and bacterial pathogenesis have been studied as separate entities. However, the scientific community is beginning to realize that not only are bacterial nutrient acquisition and utilization essential for pathogenesis, but that interfering with the pathogen-specific metabolic pathways used during infection can regulate virulence factor expression and might lead to effective breakthroughs in a variety of treatments. Editors Paul Cohen and Tyrrell Conway, who pioneered the use of metabolic mutants in competitive colonization assays, an approach now widely used to investigate the nutrition of pathogens in vivo, are uniquely qualified to advance our knowledge of this integrative field of research. They convened a group of contributors who are breaking new ground in understanding how bacterial metabolism is foundational to pathogenesis to share their expert perspectives and outlook for the future. Beginning with overviews, Metabolism and Bacterial Pathogenesis covers a wide range of diseases and both Gram-positive and -negative bacteria that serve as model systems for in vitro and in vivo investigations intracellular, respiratory, and enteric pathogens pathogen-specific nutrient acquisition in hosts mechanisms of host-driven metabolic adaptation by pathogens metabolic regulation of virulence gene expression Useful for specialists in bacterial pathogenesis and specialists in metabolism as well as molecular biologists, physicians, veterinarians, dentists, graduate and undergraduate students, and laboratory technicians, Metabolism and Bacterial Pathogenesis is also essential reading for scientists studying the microbiome.

The Future of Metabolic Engineering Book

The Future of Metabolic Engineering


  • Author : Abhishek Sharma
  • Publisher : Unknown
  • Release Date : 2022-01-20
  • Genre: Uncategoriezed
  • Pages : 372
  • ISBN 10 : 168507362X
  • Total Read : 59
  • File Size : 17,9 Mb

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The Future of Metabolic Engineering Summary:

The last two decades of scientific research have progressed to the point where metabolic engineering, which involves the modifying of metabolic pathways of animals, plants, and bacterial cells at biochemical and molecular levels, is feasible. Conceptually, metabolic engineering takes into account the identification of major blocks or control points in a metabolic pathway at the molecular level followed by removal of these limitations with the help of various cellular engineering interventions. Understanding the metabolic pathways requires appropriate experiment setup, molecular biology and biochemistry methods, computational modelling, data analysis, and interpretation to allow the researchers to manipulate them as per their needs. This book comprises a total of 12 chapters from multiple contributors of different countries around the world, including Brazil, Egypt, India, Saudi Arabia, and Turkey. This book provides deep insight into the past, present, and future of metabolic engineering in the animal, microbial, and plant system, communicating interdisciplinary research and relevant results in biochemistry, molecular biology, applied microbiology, cellular physiology, cellular nutrition in health and disease, and biochemical engineering.

Microbial Engineering for Therapeutics Book

Microbial Engineering for Therapeutics


  • Author : Mrutyunjay Suar
  • Publisher : Springer Nature
  • Release Date : 2022-11-30
  • Genre: Medical
  • Pages : 377
  • ISBN 10 : 9789811939792
  • Total Read : 81
  • File Size : 6,7 Mb

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Microbial Engineering for Therapeutics Summary:

This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.