Metabolomics for Biomedical Research Book

Metabolomics for Biomedical Research


  • Author : Jerzy Adamski
  • Publisher : Academic Press
  • Release Date : 2020-03-20
  • Genre: Medical
  • Pages : 266
  • ISBN 10 : 9780128127858
  • Total Read : 77
  • File Size : 14,7 Mb

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Metabolomics for Biomedical Research Summary:

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research. Focuses on metabolomics in translational and medical research Provides basics for, and concepts of, contemporary translational personalized medicine research with metabolomics Brings the major recent progresses on design, analytics, biostatistics and bioinformatics relating to the success of metabolomics research

Metabolomics for Biomedical Research Book

Metabolomics for Biomedical Research


  • Author : Jerzy Adamski, PhD
  • Publisher : Academic Press
  • Release Date : 2020-04-04
  • Genre: Medical
  • Pages : 266
  • ISBN 10 : 9780128127841
  • Total Read : 81
  • File Size : 5,8 Mb

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Metabolomics for Biomedical Research Summary:

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research. Focuses on metabolomics in translational and medical research Provides basics for, and concepts of, contemporary translational personalized medicine research with metabolomics Brings the major recent progresses on design, analytics, biostatistics and bioinformatics relating to the success of metabolomics research

Translational Biomedical Informatics Book

Translational Biomedical Informatics


  • Author : Bairong Shen
  • Publisher : Springer
  • Release Date : 2016-10-31
  • Genre: Science
  • Pages : 332
  • ISBN 10 : 9789811015038
  • Total Read : 63
  • File Size : 9,6 Mb

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Translational Biomedical Informatics Summary:

This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Metabolomics Perspectives Book

Metabolomics Perspectives


  • Author : Jacopo Troisi
  • Publisher : Academic Press
  • Release Date : 2022-03-15
  • Genre: Science
  • Pages : 684
  • ISBN 10 : 9780323850636
  • Total Read : 81
  • File Size : 13,8 Mb

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Metabolomics Perspectives Summary:

Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss the main current applications and future perspectives of this emerging science. Armed with critical insights, coupled with a clear writing, the book consists of three main sections. The first one introduces the pivotal theoretical fundamentals and provides a comprehensive overview of the "wet" laboratory workflow, including protocol instructions and a detailed description of experimental methods and analytical techniques. The second section covers a wide range of topics in the context of data analysis, including guidance in exploratory analysis, supervised and unsupervised machine learning approaches and validation and optimization methods. In addition to the several examples reported in the text, the book features an R package, specifically designed to perform all the described algorithms, which is hosted on a companion website (www.metabolomicsperspectives.com) together with several sets of available metabolomic data. Finally, an extensive dissertation describes the latest advances and the major fields of interest for metabolomics applications, highlighting their crucial potentials for future biomedical research. Thus, this book represents a must-read for both experienced researchers, interested in metabolomics, and newcomers to the field. • Provides an in-depth description of the metabolomics experimental workflow and its applications in life science and biomedical research • Features chapter contributions from the greatest international experts in the field • Includes an R package and several sets of metabolomics data, hosted on a companion website

Metabolomics Book

Metabolomics


  • Author : Mahbuba Rahman
  • Publisher : Academic Press
  • Release Date : 2023-01-17
  • Genre: Science
  • Pages : 348
  • ISBN 10 : 9780323913799
  • Total Read : 67
  • File Size : 14,5 Mb

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Metabolomics Summary:

Metabolomics: A Path Towards Personalized Medicine integrates environmental factors of genomics, transcriptomics and proteomics, providing a bridge to resolve gaps between fundamental science and applications in clinical medicine and population health. The concept of personalized medicine or precision medicine is of great interest in biomedical research as it helps bring about new drug discovery and biomarker identification. In addition, it helps clinicians prescribe the right medicine to the right person with maximum efficacy and minimum toxicity, allowing clinicians to further predict the susceptibility to disease onset of vulnerable populations. The book is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for the identification of disease and therapeutic targets. Gives insights on the importance of personalized medicine in clinical and research environments Provides the principles of metabolomics Presents applications of metabolomics in biomarker identification and drug discovery

High Throughput Metabolomics Book

High Throughput Metabolomics


  • Author : Angelo D'Alessandro
  • Publisher : Humana
  • Release Date : 2020-06-06
  • Genre: Science
  • Pages : 459
  • ISBN 10 : 1493992384
  • Total Read : 76
  • File Size : 15,5 Mb

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High Throughput Metabolomics Summary:

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Advancements of Mass Spectrometry in Biomedical Research Book

Advancements of Mass Spectrometry in Biomedical Research


  • Author : Alisa G. Woods
  • Publisher : Springer
  • Release Date : 2019-07-25
  • Genre: Science
  • Pages : 813
  • ISBN 10 : 9783030159504
  • Total Read : 68
  • File Size : 18,9 Mb

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Advancements of Mass Spectrometry in Biomedical Research Summary:

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.

Metabolomics Book

Metabolomics


  • Author : M. Tomita
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-06-18
  • Genre: Science
  • Pages : 256
  • ISBN 10 : 9784431280552
  • Total Read : 89
  • File Size : 5,9 Mb

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Metabolomics Summary:

Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.