Mathematics of Bioinformatics Book

Mathematics of Bioinformatics


  • Author : Matthew He
  • Publisher : John Wiley & Sons
  • Release Date : 2011-03-16
  • Genre: Computers
  • Pages : 298
  • ISBN 10 : 1118099524
  • Total Read : 66
  • File Size : 15,6 Mb

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Mathematics of Bioinformatics Summary:

Mathematics of Bioinformatics: Theory, Methods, andApplications provides a comprehensive format forconnecting and integrating information derived from mathematicalmethods and applying it to the understanding of biologicalsequences, structures, and networks. Each chapter is divided into anumber of sections based on the bioinformatics topics and relatedmathematical theory and methods. Each topic of the section iscomprised of the following three parts: an introduction to thebiological problems in bioinformatics; a presentationof relevant topics of mathematical theory and methods to thebioinformatics problems introduced in the first part; anintegrative overview that draws the connections and interfacesbetween bioinformatics problems/issues and mathematicaltheory/methods/applications.

Mathematical and Computational Methods and Algorithms in Biomechanics Book

Mathematical and Computational Methods and Algorithms in Biomechanics


  • Author : Jirí Nedoma
  • Publisher : John Wiley & Sons
  • Release Date : 2011-06-09
  • Genre: Science
  • Pages : 592
  • ISBN 10 : 1118006461
  • Total Read : 88
  • File Size : 7,6 Mb

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Mathematical and Computational Methods and Algorithms in Biomechanics Summary:

Cutting-edge solutions to current problems in orthopedics, supported by modeling and numerical analysis Despite the current successful methods and achievements of good joint implantations, it is essential to further optimize the shape of implants so they may better resist extreme long-term mechanical demands. This book provides the orthopedic, biomechanical, and mathematical basis for the simulation of surgical techniques in orthopedics. It focuses on the numerical modeling of total human joint replacements and simulation of their functions, along with the rigorous biomechanics of human joints and other skeletal parts. The book includes: An introduction to the anatomy and biomechanics of the human skeleton, biomaterials, and problems of alloarthroplasty The definition of selected simulated orthopedic problems Constructions of mathematical model problems of the biomechanics of the human skeleton and its parts Replacement parts of the human skeleton and corresponding mathematical model problems Detailed mathematical analyses of mathematical models based on functional analysis and finite element methods Biomechanical analyses of particular parts of the human skeleton, joints, and corresponding replacements A discussion of the problems of data processing from nuclear magnetic resonance imaging and computer tomography This timely book offers a wealth of information on the current research in this field. The theories presented are applied to specific problems of orthopedics. Numerical results are presented and discussed from both biomechanical and orthopedic points of view and treatment methods are also briefly addressed. Emphasis is placed on the variational approach to the investigated model problems while preserving the orthopedic nature of the investigated problems. The book also presents a study of algorithmic procedures based on these simulation models. This is a highly useful tool for designers, researchers, and manufacturers of joint implants who require the resul

Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics Book

Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics


  • Author : Yi Pan
  • Publisher : John Wiley & Sons
  • Release Date : 2013-11-12
  • Genre: Medical
  • Pages : 536
  • ISBN 10 : 9781118345788
  • Total Read : 59
  • File Size : 16,8 Mb

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Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics Summary:

Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics An in-depth look at the latest research, methods, and applications in the field of protein bioinformatics This book presents the latest developments in protein bioinformatics, introducing for the first time cutting-edge research results alongside novel algorithmic and AI methods for the analysis of protein data. In one complete, self-contained volume, Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics addresses key challenges facing both computer scientists and biologists, arming readers with tools and techniques for analyzing and interpreting protein data and solving a variety of biological problems. Featuring a collection of authoritative articles by leaders in the field, this work focuses on the analysis of protein sequences, structures, and interaction networks using both traditional algorithms and AI methods. It also examines, in great detail, data preparation, simulation, experiments, evaluation methods, and applications. Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics: Highlights protein analysis applications such as protein-related drug activity comparison Incorporates salient case studies illustrating how to apply the methods outlined in the book Tackles the complex relationship between proteins from a systems biology point of view Relates the topic to other emerging technologies such as data mining and visualization Includes many tables and illustrations demonstrating concepts and performance figures Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics is an essential reference for bioinformatics specialists in research and industry, and for anyone wishing to better understand the rich field of protein bioinformatics.

Rough Fuzzy Pattern Recognition Book

Rough Fuzzy Pattern Recognition


  • Author : Pradipta Maji
  • Publisher : John Wiley & Sons
  • Release Date : 2012-02-14
  • Genre: Technology & Engineering
  • Pages : 312
  • ISBN 10 : 9781118004401
  • Total Read : 64
  • File Size : 10,9 Mb

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Rough Fuzzy Pattern Recognition Summary:

Learn how to apply rough-fuzzy computing techniques to solve problems in bioinformatics and medical image processing Emphasizing applications in bioinformatics and medical image processing, this text offers a clear framework that enables readers to take advantage of the latest rough-fuzzy computing techniques to build working pattern recognition models. The authors explain step by step how to integrate rough sets with fuzzy sets in order to best manage the uncertainties in mining large data sets. Chapters are logically organized according to the major phases of pattern recognition systems development, making it easier to master such tasks as classification, clustering, and feature selection. Rough-Fuzzy Pattern Recognition examines the important underlying theory as well as algorithms and applications, helping readers see the connections between theory and practice. The first chapter provides an introduction to pattern recognition and data mining, including the key challenges of working with high-dimensional, real-life data sets. Next, the authors explore such topics and issues as: Soft computing in pattern recognition and data mining A mathematical framework for generalized rough sets, incorporating the concept of fuzziness in defining the granules as well as the set Selection of non-redundant and relevant features of real-valued data sets Selection of the minimum set of basis strings with maximum information for amino acid sequence analysis Segmentation of brain MR images for visualization of human tissues Numerous examples and case studies help readers better understand how pattern recognition models are developed and used in practice. This text—covering the latest findings as well as directions for future research—is recommended for both students and practitioners working in systems design, pattern recognition, image analysis, data mining, bioinformatics, soft computing, and computational intelligence.

Pattern Recognition in Computational Molecular Biology Book

Pattern Recognition in Computational Molecular Biology


  • Author : Mourad Elloumi
  • Publisher : John Wiley & Sons
  • Release Date : 2015-11-30
  • Genre: Technology & Engineering
  • Pages : 656
  • ISBN 10 : 9781119078852
  • Total Read : 86
  • File Size : 17,9 Mb

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Pattern Recognition in Computational Molecular Biology Summary:

A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.

Classification Analysis of DNA Microarrays Book

Classification Analysis of DNA Microarrays


  • Author : Leif E. Peterson
  • Publisher : John Wiley & Sons
  • Release Date : 2013-06-24
  • Genre: Computers
  • Pages : 736
  • ISBN 10 : 9780470170816
  • Total Read : 91
  • File Size : 18,7 Mb

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Classification Analysis of DNA Microarrays Summary:

Wiley Series in Bioinformatics: Computational Techniques and Engineering Yi Pan and Albert Y. Zomaya, Series Editors Wide coverage of traditional unsupervised and supervised methods and newer contemporary approaches that help researchers handle the rapid growth of classification methods in DNA microarray studies Proliferating classification methods in DNA microarray studies have resulted in a body of information scattered throughout literature, conference proceedings, and elsewhere. This book unites many of these classification methods in a single volume. In addition to traditional statistical methods, it covers newer machine-learning approaches such as fuzzy methods, artificial neural networks, evolutionary-based genetic algorithms, support vector machines, swarm intelligence involving particle swarm optimization, and more. Classification Analysis of DNA Microarrays provides highly detailed pseudo-code and rich, graphical programming features, plus ready-to-run source code. Along with primary methods that include traditional and contemporary classification, it offers supplementary tools and data preparation routines for standardization and fuzzification; dimensional reduction via crisp and fuzzy c-means, PCA, and non-linear manifold learning; and computational linguistics via text analytics and n-gram analysis, recursive feature extraction during ANN, kernel-based methods, ensemble classifier fusion. This powerful new resource: Provides information on the use of classification analysis for DNA microarrays used for large-scale high-throughput transcriptional studies Serves as a historical repository of general use supervised classification methods as well as newer contemporary methods Brings the reader quickly up to speed on the various classification methods by implementing the programming pseudo-code and source code provided in the book Describes implementation methods that help shorten discovery times Classification Analysis of DNA Microarrays is useful for profe

Computational Methods for Next Generation Sequencing Data Analysis Book

Computational Methods for Next Generation Sequencing Data Analysis


  • Author : Ion Mandoiu
  • Publisher : John Wiley & Sons
  • Release Date : 2016-09-12
  • Genre: Computers
  • Pages : 464
  • ISBN 10 : 9781119272168
  • Total Read : 84
  • File Size : 14,8 Mb

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Computational Methods for Next Generation Sequencing Data Analysis Summary:

Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, var

Multiple Biological Sequence Alignment Book

Multiple Biological Sequence Alignment


  • Author : Ken Nguyen
  • Publisher : John Wiley & Sons
  • Release Date : 2016-06-10
  • Genre: Computers
  • Pages : 256
  • ISBN 10 : 9781119272458
  • Total Read : 93
  • File Size : 7,9 Mb

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Multiple Biological Sequence Alignment Summary:

Covers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search. This book contains 11 chapters, with Chapter 1 providing basic information on biological sequences. Next, Chapter 2 contains fundamentals in pair-wise sequence alignment, while Chapters 3 and 4 examine popular existing quantitative models and practical clustering techniques that have been used in multiple sequence alignment. Chapter 5 describes, characterizes and relates many multiple sequence alignment models. Chapter 6 describes how traditionally phylogenetic trees have been constructed, and available sequence knowledge bases can be used to improve the accuracy of reconstructing phylogeny trees. Chapter 7 covers the latest methods developed to improve the run-time efficiency of multiple sequence alignment. Next, Chapter 8 covers several popular existing multiple sequence alignment server and services, and Chapter 9 examines several multiple sequence alignment techniques that have been developed to handle short sequences (reads) produced by the Next Generation Sequencing technique (NSG). Chapter 10 describes a Bioinformatics application using multiple sequence alignment of short reads or whole genomes as input. Lastly, Chapter 11 provides a review of RNA and protein secondary structure prediction using the evolution information inferred from multiple sequence alignments. • Covers the full spectrum of the field, from alignment algorithms to scoring methods, practical techniques, and alignment tools and their evaluations • Describes theories and developments of scoring functions and scoring matrices •Examines phylogeny estimation and large-scale homology search Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Applications is a reference for resear