Inborn Errors of Immunity Book

Inborn Errors of Immunity


  • Author : Asghar Aghamohammadi
  • Publisher : Academic Press
  • Release Date : 2021-02-01
  • Genre: Medical
  • Pages : 394
  • ISBN 10 : 9780128231890
  • Total Read : 63
  • File Size : 9,6 Mb

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Inborn Errors of Immunity Summary:

Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings. Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field • Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines • Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways • Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas • Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases

Stiehm s Immune Deficiencies Book

Stiehm s Immune Deficiencies


  • Author : Kathleen E Sullivan
  • Publisher : Academic Press
  • Release Date : 2014-08-08
  • Genre: Medical
  • Pages : 1156
  • ISBN 10 : 9780124058606
  • Total Read : 92
  • File Size : 15,5 Mb

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Stiehm s Immune Deficiencies Summary:

Stiehm's Immune Deficiencies focuses on immunodeficiencies in children and adults. This book covers the many advances in the study of immunodeficiency. Stiehm's Immune Deficiencies includes 62 chapters covering topics such as newly described syndromes, genetic diagnosis, molecular abnormalities, newborn screening, and current therapies. Provides practical guidance to practitioners dealing with the day-to-day issues of diagnosis and management of immune deficient patients Covers both clinical management and scientific advances in one place Includes newly described disorders in various periodic updates to maintain the breadth of the reference

Inborn Errors of Immunity and Phagocytosis Book

Inborn Errors of Immunity and Phagocytosis


  • Author : Flemming Güttler
  • Publisher : Springer
  • Release Date : 2012-02-13
  • Genre: Medical
  • Pages : 391
  • ISBN 10 : 9401161992
  • Total Read : 74
  • File Size : 9,9 Mb

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Inborn Errors of Immunity and Phagocytosis Summary:

The rapid growth of immunology has greatly increased our understanding of disease; this growth has also generated a subject which at times appears separated from some of the basic medical sciences. Recent studies in the areas of purine metabolism and of polymorphonuclear neutrophil phago cyte function have, however, linked immunology and clinical medicine with biochemistry. The precise defects of the inborn errors of metabolism have now provided good evidence for the importance of purine metabolism specifically the enzymes adenosine deaminase and nucleoside phosphorylase in lymphocyte function. In view of this and the steady advance of clinical and biochemical investigation of the polymorphonuclear neutrophil phago cyte, it appeared timely to review the inborn errors of immunity and phagocytosis at the fifteenth annual symposium of the Society for the Study of Inborn Errors of Metabolism at Elsinore, Denmark on September II-14th, I~77. The papers presented at that meeting form the basis of this volume which brings together contributions from immunologists, biochemists and clinicians. This interdisciplinary communication should be helpful to those concerned with immune function in their patients or in the laboratory. The book is divided into four sections, One: defects of cell-mediated immunity, Two: enzyme defects and immunodeficiency, Three: disorders of non-specific immunity and Four: screening for immunodeficiency. Section One contains two reviews, one on immunodeficiency from Robert Good's group in New York and another on the genetics of the immune system from Arne Svejgaard of Copenhagen.

The Inflammasomes Book

The Inflammasomes


  • Author : Isabelle Couillin
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-07-02
  • Genre: Medical
  • Pages : 226
  • ISBN 10 : 9783034801485
  • Total Read : 69
  • File Size : 18,7 Mb

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The Inflammasomes Summary:

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

Primary Immunodeficiency Disorders Book

Primary Immunodeficiency Disorders


  • Author : Lisa Kobrynski
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-11-22
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9780323654425
  • Total Read : 82
  • File Size : 20,6 Mb

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Primary Immunodeficiency Disorders Summary:

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.

Cellular Primary Immunodeficiencies Book

Cellular Primary Immunodeficiencies


  • Author : Mario Milco D'Elios
  • Publisher : Springer Nature
  • Release Date : 2021-06-10
  • Genre: Medical
  • Pages : 513
  • ISBN 10 : 9783030701079
  • Total Read : 69
  • File Size : 5,6 Mb

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Cellular Primary Immunodeficiencies Summary:

This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.

Primary Immunodeficiency Diseases Book

Primary Immunodeficiency Diseases


  • Author : Nima Rezaei
  • Publisher : Springer
  • Release Date : 2016-11-30
  • Genre: Medical
  • Pages : 582
  • ISBN 10 : 9783662529096
  • Total Read : 88
  • File Size : 7,7 Mb

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Primary Immunodeficiency Diseases Summary:

The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Cancer Immunology Book

Cancer Immunology


  • Author : Nima Rezaei
  • Publisher : Springer Nature
  • Release Date : 2020-01-03
  • Genre: Medical
  • Pages : 802
  • ISBN 10 : 9783030308452
  • Total Read : 64
  • File Size : 18,9 Mb

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Cancer Immunology Summary:

This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field. In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging. Cancer Immunology: A Translational Medicine Context will be of special value to clinical immunologists, hematologists, and oncologists.