Haschek and Rousseaux s Handbook of Toxicologic Pathology Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology


  • Author : Wanda M. Haschek
  • Publisher : Academic Press
  • Release Date : 2021-10-20
  • Genre: Medical
  • Pages : 1152
  • ISBN 10 : 9780128218297
  • Total Read : 80
  • File Size : 8,9 Mb

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Summary:

Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Handbook of Toxicologic Pathology Book

Handbook of Toxicologic Pathology


  • Author : Wanda M. Haschek
  • Publisher : Elsevier
  • Release Date : 2013-10-22
  • Genre: Medical
  • Pages : 1127
  • ISBN 10 : 9781483288611
  • Total Read : 79
  • File Size : 7,5 Mb

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Handbook of Toxicologic Pathology Summary:

This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come. Comprehensive, "user friendly" reference text on toxicologic pathology Large, easy-to-use 8 1/2" x 11", double-column format Systematic approach to each organ or system More than 500 illustrations and 90 tables complement the text Over 2,000 references for easy access to the primary literature Unique chapters written by leading authorities

Haschek and Rousseaux s Handbook of Toxicologic Pathology  Volume 2 Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 2


  • Author : Wanda M. Haschek-Hock
  • Publisher : Academic Press
  • Release Date : 2023-02-01
  • Genre: Medical
  • Pages : 0
  • ISBN 10 : 9780323910521
  • Total Read : 68
  • File Size : 6,8 Mb

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 2 Summary:

Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety. Previous chapters on such topics as drug discovery and development, toxicity and carcinogenicity testing, report preparation, and risk assessment and communication have undergone extensive revision that includes in-depth discussion of new developments in the field. New chapters consider fundamental attributes for additional product classes including protein therapeutics, nucleic acid pharmaceutical agents, gene therapy and gene editing, stem cell and other cell therapies, vaccines, agricultural and bulk chemicals, and assigning adversity. Chapters dealing with product-specific practices address pathology and regulatory issues. Chapters offer high-quality and up-to-date content in a trusted work written by the collaborative efforts of many leadi

Haschek and Rousseaux s Handbook of Toxicologic Pathology Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology


  • Author : Wanda M. Haschek
  • Publisher : Academic Press
  • Release Date : 2013-05-01
  • Genre: Medical
  • Pages : 3054
  • ISBN 10 : 9780124157651
  • Total Read : 69
  • File Size : 9,8 Mb

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Summary:

Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Haschek and Rousseaux s Handbook of Toxicologic Pathology Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology


  • Author : Wanda M. Haschek
  • Publisher : Elsevier
  • Release Date : 2001-10-16
  • Genre: Medical
  • Pages : 2421
  • ISBN 10 : 9780080491448
  • Total Read : 61
  • File Size : 14,9 Mb

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Summary:

A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environment

Haschek and Rousseaux s Handbook of Toxicologic Pathology  Volume 3 Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 3


  • Author : Wanda M. Haschek-Hock
  • Publisher : Elsevier
  • Release Date : 2023-02-01
  • Genre: Medical
  • Pages : 0
  • ISBN 10 : 9780443161544
  • Total Read : 94
  • File Size : 15,6 Mb

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 3 Summary:

Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 3,"Environmental Toxicologic Pathology and Major Toxicant Classes,’’ covers the toxicologic pathology of major classes of environmental toxicants. Other volumes in this work round out the depth and breadth of coverage. Volume 1, Principles and the Practice of Toxicologic Pathology, covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment. Volumes 4 and 5 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. Provides updated and revised chapters for in-depth discussions of toxicologic pathology in protection of the environment and food supply Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of

A Comprehensive Guide to Toxicology in Preclinical Drug Development Book

A Comprehensive Guide to Toxicology in Preclinical Drug Development


  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2012-11-02
  • Genre: Medical
  • Pages : 904
  • ISBN 10 : 9780123878151
  • Total Read : 85
  • File Size : 6,8 Mb

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A Comprehensive Guide to Toxicology in Preclinical Drug Development Summary:

A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. Intended as a comprehensive resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations (CRO), this book will discuss discovery toxicology and the international guidelines for safety evaluation and present both traditional and nontraditional toxicology models. By incorporating the latest research in this area and featuring real-life examples and scenarios, this reference is a complete and practical guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields. Includes the latest research in preclinical drug testing and international guidelines. Covers preclinical toxicology in small molecules and biologics in one single source. Incorporates real-life case studies and examples and offers readers a practical resource that outlines day-to-day activities and experiences in preclinical toxicology.

Clinical Toxicology Testing Book

Clinical Toxicology Testing


  • Author : Barbarajean Magnani
  • Publisher : Unknown
  • Release Date : 2020
  • Genre: Toxicity testing
  • Pages : 375
  • ISBN 10 : 1941096506
  • Total Read : 69
  • File Size : 12,9 Mb

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Clinical Toxicology Testing Summary:

"A comprehensive overview of clinical laboratory toxicology services and analytes"--