DNA Damage  DNA Repair and Disease Book

DNA Damage DNA Repair and Disease


  • Author : Miral Dizdaroglu
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-11-19
  • Genre: Science
  • Pages : 480
  • ISBN 10 : 9781839162565
  • Total Read : 83
  • File Size : 7,7 Mb

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DNA Damage DNA Repair and Disease Summary:

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

DNA Damage and Repair Book

DNA Damage and Repair


  • Author : A. Castellani
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-09
  • Genre: Science
  • Pages : 383
  • ISBN 10 : 9781475750164
  • Total Read : 69
  • File Size : 5,6 Mb

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DNA Damage and Repair Summary:

The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such an exchange among scientists representing many fields of endeavor and many countries. The 37 manuscripts in this volume, presented by the invited spea kers during the four and half days of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en dogenous oxidative damages. The Congress and its Proceedings are dedicated to two international leaders in the field of DNA damage and repair, Alexander Hollaender of the United States and Adriano Buzzati Traverso of Italy. Hollaender, who died in December 1986, was one of the first investigators to recognize the damage to DNA was important in cell killing and mutagenesis. His early work indicated that cells could recover from radiation injury.

DNA Repair and Mutagenesis Book

DNA Repair and Mutagenesis


  • Author : Errol C. Friedberg
  • Publisher : American Society for Microbiology Press
  • Release Date : 2005-11-22
  • Genre: Science
  • Pages : 2845
  • ISBN 10 : 9781555813192
  • Total Read : 60
  • File Size : 9,6 Mb

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DNA Repair and Mutagenesis Summary:

An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Molecular Biology of the Cell Book
Score: 4.5
From 5 Ratings

Molecular Biology of the Cell


  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 0815332181
  • Total Read : 84
  • File Size : 17,6 Mb

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Molecular Biology of the Cell Summary:

DNA Repair and Cancer Book

DNA Repair and Cancer


  • Author : Srinivasan Madhusudan
  • Publisher : CRC Press
  • Release Date : 2013-01-22
  • Genre: Medical
  • Pages : 718
  • ISBN 10 : 9781466577442
  • Total Read : 81
  • File Size : 16,8 Mb

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DNA Repair and Cancer Summary:

DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.

Mechanisms of DNA Damage and Repair Book

Mechanisms of DNA Damage and Repair


  • Author : Michael G. Simic
  • Publisher : Unknown
  • Release Date : 2014-09-01
  • Genre: Uncategoriezed
  • Pages : 596
  • ISBN 10 : 1461594634
  • Total Read : 67
  • File Size : 9,9 Mb

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Mechanisms of DNA Damage and Repair Summary:

DNA Damage  DNA Repair and Disease Book

DNA Damage DNA Repair and Disease


  • Author : Miral Dizdaroglu
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-11-19
  • Genre: Science
  • Pages : 400
  • ISBN 10 : 9781839160868
  • Total Read : 61
  • File Size : 12,8 Mb

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DNA Damage DNA Repair and Disease Summary:

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

Mechanisms of DNA Damage and Repair Book

Mechanisms of DNA Damage and Repair


  • Author : David S. Bergtold
  • Publisher : Springer
  • Release Date : 1986-06-30
  • Genre: Science
  • Pages : 604
  • ISBN 10 : UOM:39015011474486
  • Total Read : 64
  • File Size : 20,5 Mb

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Mechanisms of DNA Damage and Repair Summary:

This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.