Direct Nose to Brain Drug Delivery Book

Direct Nose to Brain Drug Delivery


  • Author : Chandrakantsing Pardeshi
  • Publisher : Academic Press
  • Release Date : 2021-06-16
  • Genre: Business & Economics
  • Pages : 554
  • ISBN 10 : 9780128225233
  • Total Read : 77
  • File Size : 12,9 Mb

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Direct Nose to Brain Drug Delivery Summary:

Direct Nose-to-Brain Drug Delivery provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration and includes an overview on the toxicity aspects of the various materials used to develop the direct nose-to-brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. This book is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose-to-brain Discusses pharmaceutical and biomedical applications after nose-to-brain delivery of therapeutic pharmaceuticals and biologicals

Direct Nose to Brain Drug Delivery Book

Direct Nose to Brain Drug Delivery


  • Author : Chandrakantsing Pardeshi
  • Publisher : Elsevier
  • Release Date : 2021-06-18
  • Genre: Business & Economics
  • Pages : 554
  • ISBN 10 : 9780128225226
  • Total Read : 91
  • File Size : 6,6 Mb

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Direct Nose to Brain Drug Delivery Summary:

Direct Nose-to-Brain Drug Delivery provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration and includes an overview on the toxicity aspects of the various materials used to develop the direct nose-to-brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. This book is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose-to-brain Discusses pharmaceutical and biomedical applications after nose-to-brain delivery of therapeutic pharmaceuticals and biologicals

Neuro AIDS Book

Neuro AIDS


  • Author : Alireza Minagar
  • Publisher : Nova Publishers
  • Release Date : 2006
  • Genre: Medical
  • Pages : 280
  • ISBN 10 : 159454610X
  • Total Read : 88
  • File Size : 12,8 Mb

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Neuro AIDS Summary:

During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.

Topical Applications and the Mucosa Book

Topical Applications and the Mucosa


  • Author : C. Surber
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2011-02-10
  • Genre: Medical
  • Pages : 174
  • ISBN 10 : 9783805596169
  • Total Read : 87
  • File Size : 5,5 Mb

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Topical Applications and the Mucosa Summary:

Mucosal membranes have unique anatomical and physiological properties -- differing from those of the keratinized epithelium -- which affect drug or chemical absorption. This makes the diagnosis and treatment of diseases of the mucosa a challenge to dermatologists as well as gynecologists, since many conditions are difficult to recognize and well-established principles of skin disease treatment do not apply to the mucosa. This volume is exclusively devoted to the mucosal membrane and delivers a better understanding of this distinctive area. Subsequently to introductory chapters on the morphology and physiology of the mucosa, the topical treatment of impaired mucosal membranes is discussed. A third section covers the wide spectrum of consumer products applied on mucosal surfaces. Finally, the safety of products for mucosal membranes is reviewed.Providing an excellent summary and review of the latest findings and topical applications, this book will be of great value to physicians and clinicians in dermatology or gynecology, pharmacists, scientists and toxicologists who are involved in the development of products for mucosal membranes.

Brain Targeted Drug Delivery Systems Book

Brain Targeted Drug Delivery Systems


  • Author : Huile Gao
  • Publisher : Academic Press
  • Release Date : 2018-09-20
  • Genre: Medical
  • Pages : 499
  • ISBN 10 : 9780128140024
  • Total Read : 81
  • File Size : 5,8 Mb

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Brain Targeted Drug Delivery Systems Summary:

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers Discusses key points in developing brain targeting drug delivery systems Summarizes and presents currently available strategies for brain targeting drug delivery Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research

Advances in Medical and Surgical Engineering Book

Advances in Medical and Surgical Engineering


  • Author : Waqar Ahmed
  • Publisher : Academic Press
  • Release Date : 2020-03-21
  • Genre: Technology & Engineering
  • Pages : 418
  • ISBN 10 : 9780128226032
  • Total Read : 88
  • File Size : 7,6 Mb

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Advances in Medical and Surgical Engineering Summary:

Advances in Medical and Surgical Engineering integrates the knowledge and experience of experts from academia and practicing surgeons working with patients. The cutting-edge progress in medical technology applications is making the traditional line between engineering and medical science ever thinner. This is an excellent resource for biomedical engineers working in industry and academia on developing medical technologies. It covers challenges in the application of technology in the clinic with views from an editorial team that is highly experienced in engineering, biomaterials, surgical practice, biomedical science and technology, and that has a proven track record of publishing applied biomedical science and technology. For medical practitioners, this book covers advances in technology in their domain. For students, this book identifies the opportunities of research based on the reviews of utilization of current technologies. The content in this book can also be of interest to policymakers, research funding agencies, and libraries, that are contributing to development of medical technologies. Covers circulatory support, aortic valve implantation and microvascular antestmosis Explores arthroplasty of both the knee and the shoulder Includes tribology of materials, laser treatment and machining of biomaterial

Nanotechnology Methods for Neurological Diseases and Brain Tumors Book

Nanotechnology Methods for Neurological Diseases and Brain Tumors


  • Author : Yasemin Gürsoy Özdemir
  • Publisher : Academic Press
  • Release Date : 2017-07-14
  • Genre: Medical
  • Pages : 378
  • ISBN 10 : 9780128038000
  • Total Read : 81
  • File Size : 12,8 Mb

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Nanotechnology Methods for Neurological Diseases and Brain Tumors Summary:

Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors. Comprehensive guide for up-to-date views on the latest advances in targeted treatment strategies for brain tumors and neurological diseases Designed with a multidisciplinary approach that links neurology, neuro-oncology and nanoscience to drug delivery to the brain with an emphasis on the blood-brain-barrier Written in a language that makes it easy to understand nanotechnology drug delivery techniques Presents a unique book that also covers advanced treatment approaches of neurological diseases and brain tumors

Drug and Gene Delivery to the Central Nervous System for Neuroprotection Book

Drug and Gene Delivery to the Central Nervous System for Neuroprotection


  • Author : Hari S. Sharma
  • Publisher : Springer
  • Release Date : 2017-06-14
  • Genre: Medical
  • Pages : 228
  • ISBN 10 : 331957695X
  • Total Read : 68
  • File Size : 16,5 Mb

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Drug and Gene Delivery to the Central Nervous System for Neuroprotection Summary:

This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of nanotechnological advances in therapeutic medicine. This book also: Broadens readers’ understanding of viral vector gene delivery to the brain for treating neurogenetic diseases as well as targeted gene delivery into the brain using microbubble-facilitated focused ultrasound Covers in detail the latest developments in delivering therapeutic materials, such as siRNA delivery to the brain for treating neurological diseases, neuroprotective effects of gelatin nanoparticles in stroke, and nanowired drug delivery for brain diseases, heat stroke, and CNS injury Enriches understanding of new technologies for delivering therapeutic materials treating Alzheimer’s Disease, including targeted nanodrug delivery through the blood-brain barrier and the superior neuroprotective effects of nanowired drug delivery in Alzheimer’s Disease