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This text is a comprehensive introductory-level guide to invasive cardiac EP studies. Its focus is to enable the reader to understand and interpret the recording and stimulation techniques used during an EP study.
This book offers a comprehensive review of clinical cardiac electrophysiology in a question and answer format. Chapters contain over 200 questions divided into 9 chapters, each organized by cardiac electrophysiology topic. Each question is followed by the correct answer with a detailed explanation along with references for further reading. Important concepts are highlighted and supported by over 200 illustrations and high resolution images. The book addresses a broad range of topics that are important when studying for the initial certification or recertification of the clinical cardiac electrophysiology board examination. It is also highly relevant for daily clinical practice in cardiology and cardiac electrophysiology. Topics covered in the book include: Review of basic and clinical cardiac electrophysiology principles associated with cardiac arrhythmias The evaluation and management of patients with cardiac rhythm disorders Review of pharmacologic and nonpharmacologic therapies for the treatment of arrhythmias Clinical indications, fundamental principles and electrical characteristics of implantable cardiac electronic devices such as pacemakers and defibrillators Clinical, electrocardiographic, and electrophysiologic characteristics of specific cardiac arrhythmia syndromes Cardiac Electrophysiology Board Review is a must-have resource for cardiology and cardiac electrophysiology trainees as well as attending physicians preparing for the certification or recertification examination. It may also be a useful guide for cardiologists, cardiac electrophysiologists and all clinicians who wish to further their understanding of heart rhythm disorders.
This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.
Fully revised and updated, Dr. Josephson's classic text provides a thorough understanding of the mechanisms of cardiac arrhythmias and the therapeutic interventions used to treat arrhythmias. This edition has a new full-color design, and a companion Web site offers the fully searchable text.
The Essential Visual Guide to Basic Cardiac Electrophysiology Cardiac Electrophysiology: A Visual Guide for Nurses, Techs, and Fellows, Second Edition fulfills the need of allied health personnel and new fellows for a practical, hands-on pictorial guide that clearly illustrates the essential concepts of clinical cardiac electrophysiology. More than 85 high-quality tracings, diagrams, fluoroscopic images, and electroanatomic maps, accompanied by detailed discussions of each image, offer a fundamental understanding of cardiac electrophysiology equipment, principles, and procedures: • Catheter placement, hardware connections, and intracardiac signals • Normal electrogram sequences associated with sinus rhythm • Methodologies used to uncover the mechanisms of common clinical tachycardias Authored by a team of experts, Cardiac Electrophysiology: A Visual Guide for Nurses, Techs, and Fellows, Second Edition is an invaluable resource for a complex technology, providing superb guidance in acclimating new trainees and personnel to the EP laboratory and empowering them with the knowledge and skills needed to practice clinical electrophysiology. New to the Second Edition: • A new unit—Cardiac Electrical Axis • 16 video clips with a focus on electrogram sequences • An illustrated glossary and abbreviations list • A free eBook included
The gold standard in electrophysiology, Dr. Josephson's book brings to light current relevant practices aimed at medical internists, clinical cardiologists, and electrophysiologists, emphasizing the capabilities and limitations of clinical cardiac electrophysiology techniques. Thoroughly revised, the Third Edition includes increased coverage of catheter ablation and the latest information on new catheters and computers that measure electrical activity in the heart. Full-color heart maps and illustrations of electrophysiologic concepts help clarify the text. A Brandon-Hill recommended title.
Interventional Cardiac Electrophysiology is the first and only comprehensive, state-of-the-art textbook written for practitioners in multiple specialties involved in the care of the arrhythmia patient. Encompassing the entire field of interventional therapy for cardiac rhythm management, from basic science to evidence-based medicine to future directions, topics include: Technology and Therapeutic Techniques – EP techniques; imaging and radiologic technology; device and ablation technology; drug therapy.Interventional Electrophysiologic Procedures – Diagnostic and physiologic EP techniques; mapping in percutaneous catheter and surgical EP procedures; catheter and surgical ablation; device implantation and management.Clinical Indications and Evidence-based Outcomes Standards – For medical and surgical EP interventions for arrhythmias.New Directions in Interventional Electrophysiology – Hybrid therapy for atrial and ventricular arrhythmias and staged therapy. This book will be essential reading for clinicians and researchers that form the health care team for arrhythmia patients: cardiologists, adult and pediatric clinical electrophysiologists, interventional electrophysiologists, cardiac surgeons practicing arrhythmia surgery, allied health care professionals, pharmacologists, radiologists and anesthesiologists evaluating arrhythmia patients, and basic scientists from the biomedical engineering and experimental physiology disciplines. Professor Sanjeev Saksena has been involved in this arena for over three decades and has brought his experience to this textbook, assembling editorial leadership from medical and surgical cardiology to provide a global perspective on fundamentals of medical practice, evidence-based therapeutic practices, and emerging research in this field. This book includes 95 videos.
This book provides a concise overview of cardiac electrophysiology for cardiologists who are not electrophysiologists and for allied cardiovascular professionals, cardiology registrars and fellows who are new to the field. It familiarises them with the main procedures performed in the electrophysiology laboratory. Emphasis is placed on helping the reader develop a core understanding of how data is collected and interpreted in the electrophysiology laboratory, and how this is used to guide ablation for the commonest arrhythmias including AV nodal re-entry tachycardia, accessory pathways, atrial fibrillation and ventricular arrhythmias. Decoding Cardiac Electrophysiology: Understanding the Techniques and Defining the Jargon will translate some of the technical terminology and data frequently used by electrophysiologists into terms and concepts familiar to the wider cardiovascular community. This includes the interpretation of electrograms and 3D electro-anatomical maps of common arrhythmias. Accordingly, it offers a valuable resource for all non-electrophysiologists seeking a guide to the topic and for electrophysiology trainees establishing their core knowledge and skills in the field. The aim is that this should be the first book anyone new to the field should choose to read.
Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.
Widely known as the premier electrophysiology text, Josephson’s Clinical Cardiac Electrophysiology provides a thorough understanding of the mechanisms of cardiac arrhythmias and the therapeutic interventions used to treat them. Dr. David J. Callans, personally chosen and trained by Dr. Mark Josephson, continues the tradition of excellence of previous editions while bringing the text fully up to date in every area of this complex field. The sixth edition provides highly visual guidance on the electrophysiologic methodology required to define the mechanism and site of origin of arrhythmia – enabling you to choose the safest and most effective therapy for each patient.
This concise collection of electrophysiological facts prepares you to face the clinical questions surrounding arrhythmia and conduction disorders with confidence. Clear and direct, the book offers: succinct factual information supported by illustrations, tables, and references self-assessment questions for each chapter, to test your knowledge of the area Essential Cardiac Electrophysiology summarizes the fundamental information that forms the basis of the modern approach to cardiac arrhythmias, from an explanation of the electrophysiologic effects of cardiac ion channel activity to the latest information on available implantable defibrillators. All members of the cardiac care team will benefit from keeping this valuable guide close at hand.
Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure
Turn to this updated, classic text for a thorough understanding of the mechanisms of cardiac arrhythmias and the therapeutic interventions used to treat them. Josephson’s Clinical Cardiac Electrophysiology, 5th Edition delivers Dr. Mark Josephson’s unparalleled guidance on the electrophysiologic methodology required to define the mechanism and site of origin of arrhythmias – enabling you to choose the safest and most effective therapy for each patient. Features: Get comprehensive coverage of mechanisms, clinical implications, and limitations of current therapeutic interventions, including drugs, and catheter and surgical ablation. Gain a better visual understanding thanks to more than 1,100 illustrations (over 100 are new!), an increased number of 3-D color anatomical mapping images, ECG examples, photographs of equipment, and procedural diagrams. Stay up to date with information on new technologies of ablation and pitfalls of interpreting data; innovative new catheters; new drug information; and new tables summarizing SVT and VT criteria. Benefit from Dr. Josephson’s decades of experience as “the father of clinical cardiac electrophysiology,” and learn from his proven approaches and methods in this challenging area. View procedural videos and ECG tracings in motion in the accompanied eBook.
This extensively revised second edition provides a practically applicable guide for the management of cardiac arrhythmia. This subject has continued to expand rapidly, and it is therefore critical to understand the basic principles of arrhythmia mechanisms in order to assist with diagnosis and the selection of an appropriate treatment strategy. Comprehensively revised chapters cover a variety of aspects of cardiac electrophysiology in an easy-to-digest case-based format. For each case of arrhythmia, relevant illustrations, fluoroscopy images, ECGs and endocavity electrograms are used to describe the etiology, classification, clinical presentation, mechanisms, electrophysiology set up and relevant trouble-shooting procedures. New topics covered include the application of new antiarrhythmic drugs in tandem with ablation, techniques for the ablation of atrial fibrillation and electrophysiological assessments available for identifying instances of atrial tachycardia. Clinical Handbook of Cardiac Electrophysiology presents a comprehensive overview of cardiac electrophysiology, making it a valuable reference for practicing and trainee cardiac electrophysiologists, cardiologists, family practitioners, allied professionals and nurses.
Cardiac Electrophysiology: From Cell to Bedside defines the entire state of current scientific and clinical knowledge in this subspecialty. In response to the many major recent developments in the field, Drs. Zipes and Jalife have completely updated this modern classic, making the 5th Edition the most significant revision yet. From our latest understanding of ion channels, molecular genetics, and cardiac electrical activity through newly recognized syndromes, unique needs of special patient populations, and new diagnostic and therapeutic options, you'll find all the state-of-the-art guidance you need to make informed, effective clinical decisions. What's more, a significantly restructured organization, a new full-color layout, and full-text online access make reference easier than ever. Integrates the latest scientific understanding of arrhythmias with the newest clinical applications, giving you an informed basis for choosing the right treatment and management options for each patient. Synthesizes the knowledge of preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world, giving you a well-rounded, expert grasp of every issue that affects your patient management. Contains 24 new chapters (listed below) as well as exhaustive updates throughout, to keep you current with new scientific knowledge, newly discovered arrhythmia syndromes, and new diagnostic and therapeutic techniques. Developmental Regulation of Cardiac Ion Channels Neural Mechanisms of Initiating and Maintaining Arrhythmias Single Nucleotide Polymorphisms and Acquired Cardiac Arrhythmias Inheritable Sodium Channel Diseases Inheritable Potassium Channel Diseases Inheritable Diseases of Intracellular Calcium Regulation Morphological Correlates of Atrial Arrhythmias Andersen-Tawil Syndrome Timothy Syndrome Progressive Cardiac Conduction Disease Sudden Infant Death Syndrome Arrhythmias in Patient