Biomaterials for 3D Tumor Modeling Book

Biomaterials for 3D Tumor Modeling


  • Author : Subhas C. Kundu
  • Publisher : Elsevier
  • Release Date : 2020-08-22
  • Genre: Technology & Engineering
  • Pages : 772
  • ISBN 10 : 9780128181294
  • Total Read : 74
  • File Size : 8,7 Mb

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Biomaterials for 3D Tumor Modeling Summary:

Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine. Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery

Biomaterials  and Microfluidics Based Tissue Engineered 3D Models Book

Biomaterials and Microfluidics Based Tissue Engineered 3D Models


  • Author : J. Miguel Oliveira
  • Publisher : Springer Nature
  • Release Date : 2020-04-13
  • Genre: Medical
  • Pages : 175
  • ISBN 10 : 9783030365882
  • Total Read : 76
  • File Size : 20,5 Mb

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Biomaterials and Microfluidics Based Tissue Engineered 3D Models Summary:

This contributed volume reviews the latest advances on relevant 3D tissue engineered in vitro models of disease making use of biomaterials and microfluidics. The main focus of this book is on advanced biomaterials and microfluidics technologies that have been used in in vitro mimetic 3D models of human diseases and show great promise in revolutionizing personalized medicine. Readers will discover important topics involving biomaterials and microfluidics design, advanced processing techniques, and development and validation of organ- and body-on-a-chip models for bone, liver, and cancer research. An in depth discussion of microfabrication methods for microfluidics development is also provided. This work is edited by two truly multidisciplinary scientists and includes important contributions from well-known experts in their fields. The work is written for both early stage and experienced researchers, and well-established scientists enrolled in the fields of biomaterials, microfluidics, and tissue engineering, and is especially suited to those who wish to become acquainted with the principles and latest developments of in vitro models of diseases, such as professionals working in pharma, medicine, and engineering.

Cell Derived Matrices Part B Book

Cell Derived Matrices Part B


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-04-23
  • Genre: Science
  • Pages : 264
  • ISBN 10 : 9780128201756
  • Total Read : 98
  • File Size : 14,6 Mb

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Cell Derived Matrices Part B Summary:

Cell-Derived Matrices Part B, Volume 157 provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Chapters in this new release include Glaucomatous cell-derived matrices, Cardiac tissue explants decellularization, Decellularization of skin matrices for wound healing applications, Guiding axonal growth by aligned cell-derived matrices for spinal cord injury regeneration, Human Mesenchymal Stem Cell–Derived Matrices for Enhanced Osteoregeneration, Amniotic decellularized matrices, Three-Dimensional (3-D) Tissue Reconstruction without Scaffold, Tubular cell-derived matrices for TERM applications, and more. Contains contributions from leading experts in the field from across the globe Covers a wide array of topics surrounding the use of cell-derived matrices for tissue engineering and regenerative medicine applications Includes relevant, analysis-based topics, such as the quantification of mechanical properties, decellularization protocols, and innovative matrix engineering methods

Cell derived Matrices Part A Book

Cell derived Matrices Part A


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-03-26
  • Genre: Science
  • Pages : 350
  • ISBN 10 : 9780128201732
  • Total Read : 67
  • File Size : 11,6 Mb

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Cell derived Matrices Part A Summary:

Cell-Derived Matrices, Part A, Volume 156, provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Biochemical, biophysical and cell biological approaches are presented, along with sample results. Specific chapters cover Anisotropic cell-derived matrices with controlled 3D architecture, Generation of functional fluorescently-labelled cell-derived matrices by means of genetically-modified fibroblasts, Bi-layered cell-derived matrices, Engineering clinically-relevant cell-derived matrices using primary fibroblasts, Decellularized matrices for bioprinting applications, and much more. Contains contributions from leading experts in the field from across the globe Covers a wide array of topics on the use of cell-derived matrices for tissue engineering and regenerative medicine applications Includes relevant, analysis-based topics, such as quantification of the mechanical properties, decellularization protocols, and innovative matrix engineering methods

Microfluidics and Biosensors in Cancer Research Book

Microfluidics and Biosensors in Cancer Research


  • Author : David Caballero
  • Publisher : Springer Nature
  • Release Date : 2022-06-27
  • Genre: Medical
  • Pages : 599
  • ISBN 10 : 9783031040399
  • Total Read : 92
  • File Size : 19,8 Mb

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Microfluidics and Biosensors in Cancer Research Summary:

This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.

Silk Biomaterials for Tissue Engineering and Regenerative Medicine Book

Silk Biomaterials for Tissue Engineering and Regenerative Medicine


  • Author : Subhas Kundu
  • Publisher : Elsevier
  • Release Date : 2014-03-24
  • Genre: Medical
  • Pages : 582
  • ISBN 10 : 9780857097064
  • Total Read : 84
  • File Size : 18,8 Mb

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Silk Biomaterials for Tissue Engineering and Regenerative Medicine Summary:

Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area. Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering. Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering. Discusses the properties and applications of silk for medical purposes Considers pharmaceutical and cosmeceutical applications

Biofabrication and 3D Tissue Modeling Book

Biofabrication and 3D Tissue Modeling


  • Author : Dong-Woo Cho
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-01-02
  • Genre: Technology & Engineering
  • Pages : 369
  • ISBN 10 : 9781788011983
  • Total Read : 86
  • File Size : 12,7 Mb

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Biofabrication and 3D Tissue Modeling Summary:

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, it provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.