Biomaterials and Devices for the Circulatory System Book

Biomaterials and Devices for the Circulatory System


  • Author : Terence Gourlay
  • Publisher : Elsevier
  • Release Date : 2010-10-28
  • Genre: Medical
  • Pages : 400
  • ISBN 10 : 9780857090553
  • Total Read : 90
  • File Size : 9,9 Mb

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Biomaterials and Devices for the Circulatory System Summary:

Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Bioengineering and Biomaterials in Ventricular Assist Devices Book

Bioengineering and Biomaterials in Ventricular Assist Devices


  • Author : Eduardo Guy PerpĂ©tuo Bock
  • Publisher : CRC Press
  • Release Date : 2021-10-07
  • Genre: Technology & Engineering
  • Pages : 362
  • ISBN 10 : 9781000462852
  • Total Read : 75
  • File Size : 15,5 Mb

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Bioengineering and Biomaterials in Ventricular Assist Devices Summary:

Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support. FEATURES Establishes an area of intersection between engineering and medicine Shows process development from mechanical design to automation and control Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.

Characterization of Biomaterials Book

Characterization of Biomaterials


  • Author : Ming H. Wu
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-03-12
  • Genre: Science
  • Pages : 450
  • ISBN 10 : 9780128071052
  • Total Read : 66
  • File Size : 18,6 Mb

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Characterization of Biomaterials Summary:

The cardiovascular system consists of the heart and the vasculature. The physiology of the system is to circulate blood through the vasculature ensuring delivery of oxygen and vital nutrients to cells and organs in the body. Consequences of diseases disrupting normal cardiovascular function can be severe or fatal. Recent advancements in cardiovascular medicine have contributed significantly to improving life span and quality for patients by restoring normal cardiovascular function through the use of implantable devices. Examples of these cardiovascular implantable devices include endovascular stents, embolic protection devices and filters, closure devices, heart valve prostheses, cardiac rhythm management devices, such as pacemakers and defibrillators, and left ventricular assist devices. The main objective of this chapter is to provide an overview of device test methods commonly used in the development process from concept to commercialization of implantable cardiovascular devices. It is recognized that general device testing methodology and understanding for developing these cardiovascular devices can be extended to other devices as well as new product concepts under development. Developments of new medical devices are closely regulated by regulatory agencies. U.S. and international regulatory requirements for medical devices and drugs provide specific guidance for bench-top in vitro testing, in vivo animal study, clinical research, manufacturing, sterilization, and post-market surveillance for various device categories. Implantable cardiovascular devices generally fall within the Class II and Class III categories. Commercialization of these products in the United States requires FDA's Premarket Notifications (510Ks), Premarket Approvals (PMAs), or Exemptions. The design control element in the new product development procedure requires detailed documentation of design inputs and outputs as well as rational design verification through testing to ensure device funct

Minimized Cardiopulmonary Bypass Techniques and Technologies Book

Minimized Cardiopulmonary Bypass Techniques and Technologies


  • Author : Terence Gourlay
  • Publisher : Elsevier
  • Release Date : 2012-04-19
  • Genre: Medical
  • Pages : 272
  • ISBN 10 : 9780857096029
  • Total Read : 93
  • File Size : 20,7 Mb

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Minimized Cardiopulmonary Bypass Techniques and Technologies Summary:

Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative bleeding. Minimised cardiopulmonary bypass techniques use developments in perfusion technology to significantly reduce foreign surface-blood interactions to make bypass simpler and safer. This important book reviews key developments and issues relating to this promising technology. Part one covers the broad range of CPB pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces, optimal haemodilution levels, and the important issue of CPB-induced systemic inflammatory response syndrome. Part two focuses on the issues of the new equipment developed for mini-CPB, optimal myocardial protection protocols and CPB perfusate options. Part three discusses clinical issues, including patient selection, coronary and valve surgery protocols and, among others, paediatric patients. With its distinguished editors and international team of expert contributors, Minimized cardiopulmonary bypass techniques and technologies is a valuable reference for cardiac surgery teams and those researching this important technology. Covers a broad range of cardiopulmonary bypass (CPB) pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces and optimal haemodilution levels Focuses on new equipment specially developed for minimized-CPB and myocardial protection protocols Discusses clinical issues, including patient selection

Applications of Polyurethanes in Medical Devices Book

Applications of Polyurethanes in Medical Devices


  • Author : Ajay Padsalgikar
  • Publisher : William Andrew
  • Release Date : 2022-06-01
  • Genre: Technology & Engineering
  • Pages : 282
  • ISBN 10 : 9780128231685
  • Total Read : 94
  • File Size : 11,8 Mb

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Applications of Polyurethanes in Medical Devices Summary:

Applications of Polyurethanes in Medical Devices provides detailed coverage of polyurethane (PU) chemistry, processing and preparation for performant medical devices. Polyurethanes have found many uses in medical applications, due to their biocompatibility, biostability, physical properties, surface polarity, and the ability to suit the field of application. This book enables the reader to understand polyurethane and how this valuable material can be used in medical devices. Sections cover the chemistry, structure, and properties of polyurethane, with in-depth sections examining raw materials, reaction chemistry, synthesis techniques, reaction kinetics, material microstructure, and structure-property relationships. Subsequent chapters demonstrate how polyurethane can be utilized in medical device applications, examining biological properties, rheology and processing before methodical coverage explains how polyurethane may be used for each category of medical device. Finally, future directions, and safety and environmental aspects, are covered. Bridges the gap between polyurethane chemistry, processing and preparation for cutting-edge medical device applications Includes in-depth coverage of polyurethane, covering raw materials, chemistry, synthesis techniques, reaction kinetics, properties and microstructural analysis Takes a valuable and practical approach, addressing manufacturing issues and using testing and modeling to solve problems encountered in processing

Inhaler Devices Book

Inhaler Devices


  • Author : Polina Prokopovich
  • Publisher : Elsevier
  • Release Date : 2013-04-23
  • Genre: Technology & Engineering
  • Pages : 192
  • ISBN 10 : 9780857098696
  • Total Read : 88
  • File Size : 6,7 Mb

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Inhaler Devices Summary:

Given their direct impact on the health and quality of life for millions, inhalers represent a major turning point in the history of modern medicine. Inhaler devices: Fundamentals, design and drug delivery provides readers with an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development. Part one discusses the fundamentals and development of inhaler devices as well as drug formulations for inhalers. The treatment of asthma is also discussed. Part two reviews recent developments in drug formulation and nanotechnology for inhaler devices, emerging inhaler technology and possible future trends. Inhaler devices: Fundamentals, design and drug delivery is an essential design guide for good industrial practice, and will be an invaluable resource for those researching and treating conditions such as asthma; and those developing and manufacturing inhalation devices. Introduces the fundamentals of inhaler technology Discusses the history of inhalers as well as current research and development as well as possible future trends Considers the development of inhaler devices, drug formulations and discusses the treatment of asthma

Medical Devices Book

Medical Devices


  • Author : Seeram Ramakrishna
  • Publisher : Woodhead Publishing
  • Release Date : 2015-08-18
  • Genre: Medical
  • Pages : 256
  • ISBN 10 : 9780081002919
  • Total Read : 80
  • File Size : 10,9 Mb

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Medical Devices Summary:

Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors’ practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. Provides readers with a global perspective on medical device regulations Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards Includes a useful case study demonstrating the design and approval process

Microfluidic Devices for Biomedical Applications Book

Microfluidic Devices for Biomedical Applications


  • Author : Xiujun James Li
  • Publisher : Elsevier
  • Release Date : 2013-10-31
  • Genre: Technology & Engineering
  • Pages : 676
  • ISBN 10 : 9780857097040
  • Total Read : 98
  • File Size : 10,7 Mb

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Microfluidic Devices for Biomedical Applications Summary:

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering